Bicillin L-A

(penicillin G benzathine)

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Treats bacterial infections.

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Our bottom line

Bicillin L-A (penicillin G benzathine) is the first-choice treatment for syphillis. It is not as effective for treatment of other types of bacterial infections.

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    $1559.48
Quick facts about Bicillin L-A
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Effective treatment even for the more severe forms of syphilis.
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Downsides

  • Only available as a deep muscle injection, which can be painful or uncomfortable.
  • Not a good choice for more common types of bacterial infections.
  • Can cause diarrhea like most other antibiotics.
  • Can cause severe allergic reaction, especially if you have a sensitivity to penicillins.
  • Can cause fever, headache, or muscle pain during first few doses when treating syphilis.
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What to expect from Bicillin L-A, on one page

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How it works

Bicillin L-A (penicillin G benzathine) is an antibacterial. It kills bacteria by interfering with its cell wall production.

Quick facts about Bicillin L-A
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

Dosage forms

  • Injection
Tried Bicillin L-A? Write a review!

Prices and coupons

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What to expect when you take Bicillin L-A (penicillin G benzathine) for Syphilis

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  • Effectiveness
  • Full effects
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  • Possible side effects
  • Inflammatory response syndrome (Herx reaction)
  • Allergic reaction
  • Diarrhea
  • Pain and redness at site of injection
  • Rash
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Side effect rates for Bicillin L-A (penicillin G benzathine)

Risks and Warnings for Bicillin L-A (penicillin G benzathine)

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  • Bicillin L-A (penicillin G benzathine) should be an injection into the muscle. Bicillin L-A (penicillin G benzathine) is NOT injected into the vein or nerve. Injection into the vein can result in serious injury and possibly death; while injection into the nerve can cause nerve damage. Your doctor or nurse will make sure this is performed correctly.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Bicillin L-A (penicillin G benzathine)

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Pain
  • Can cause fever, headache, or muscle pain during first few doses when treating syphilis.