Percocet

(Oxycodone / Acetaminophen)

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3.8/ 5 average rating with 1399 reviewsforPercocet
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Treats moderate to severe pain.

Skip Upsides & Downsides section. Skip to side effects section.
Prescription opioids are used to treat several kinds of pain - but they carry significant risks, including addiction. Learn more about these drugs and be sure to discuss the risks with your doctor.

Our bottom line

Percocet (Oxycodone / Acetaminophen) is the strongest prescription combination pain medicine for as needed pain relief, but make sure you don't take too much acetaminophen (Tylenol) to avoid liver problems or death.

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    $1256.68
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Quick facts about Percocet
  • Drug class: Pain
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (oxycodone / acetaminophen)

Upsides

  • Combination pain medicine with an opioid component (oxycodone) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
  • Provides quick relief for moderate to severe pain to improve quality of life.
  • Generally considered stronger than Norco or other combination pain medicine for treating pain.
  • Good for as-needed, short-term use, but may be helpful to manage more long-term pain problems if used at the appropriate doses and intervals.
  • Lower rates of misuse compared to pure opioid medicines.
  • Can help you fall asleep easier.
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What to expect from Percocet, on one page

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People’s experience with Percocet

1399reviews so far. What do you think?

Downsides

  • Dizziness and drowsiness is common, but your body may adjust.
  • Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Percocet if you need.
  • All opioid containing medicines have the risk of physical dependence and possibility of withdrawal when used long-term.
  • The non-opioid part of Percocet, acetaminophen (Tylenol), has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful.
  • Relies on the users to be aware of how much acetaminophen (Tylenol) they are using since it is a very common ingredient in many prescription and non-prescription pain medicines.
  • Avoid alcohol.
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What to expect from Percocet, on one page

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How it works

Percocet (Oxycodone / Acetaminophen) is a combination pain medicine. Oxycodone is an opioid (similar to morphine) that works in the brain to lower pain perception. Acetaminophen is a non-opioid pain reliever and fever reducer.

Quick facts about Percocet
  • Drug class: Pain
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (oxycodone / acetaminophen)

Used for

Dosage forms

  • Pill
  • Oral solution
People’s experience with Percocet

1399reviews so far. What do you think?

Prices and coupons

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What to expect when you take Percocet (Oxycodone / Acetaminophen) for Pain

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
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  • Effectiveness
  • Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Upset stomach
  • Dizziness
  • Sleepiness
  • Constipation
  • Physical dependence
  • Difficulty breathing
Skip side effects section. Skip to risks and warnings section.

Side effect rates for Percocet (Oxycodone / Acetaminophen)

Risks and Warnings for Percocet (Oxycodone / Acetaminophen)

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    • Higher risk if:
    • › Current liver disease
    • › Taking with alcohol
    • › Taking other medicines with acetaminophen

    The acetaminophen component in Percocet (Oxycodone / Acetaminophen) can hurt your liver. Using more than 4000 mg of the acetaminophen (or 12 tablets of Percocet (Oxycodone / Acetaminophen) can cause serious harm to your liver that may make you need a liver transplant and can be life-threatening. Don't take more than your doctor prescribes, and avoid other medicines that have acetaminophen when using Percocet (Oxycodone / Acetaminophen).

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Pharmacist Q&A

Percocet (Oxycodone / Acetaminophen) questions for

Frequently Asked Questions

This medication treats moderate to moderately severe pain

Who is this drug for?

This medication treats moderate to moderately severe pain

Common concerns from people taking Percocet (Oxycodone / Acetaminophen)

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Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insertSee pregnancy safe medications
Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for Percocet
CWeigh risks vs. benefits
Price
  • Worth it
    Worked well
    Low hassle
    Reviewed Percoceton 5/19/2021No Script or health Insurance needed to place and order with 10% discount for all purchased. It was nice to have some from them, they offer all pain relief from oxy, tramadol, vicodine, soma, klonapin, xanax, opana, norco,..etc I just hit them at. WhatsApp only:+1(775)7735306, Call/Text:+1(775)7735306, Wickr or Kik: peterking2014. Email: peterkings2014@gmail.com. Message code: (Med16) Discreet Delivery
    38
    Woman
    A few months
    Pain (moderate to moderately-severe)
  • Worth it
    Worked well
    Reviewed Percoceton 4/15/2021No Script or health Insurance needed to place and order with 10% discount for all purchased. It was nice to have some from them, I just hit them at. WhatsApp only:+1(775)7735306, Call/Text:+1(775)7735306, Wickr or Kik: peterking2014. Email: peterkings2014@gmail.com. Message code: (Med16) Discreet Delivery
    30
Alcohol
  • Avoid alcohol.
  • Worth it
    Worked so-so
    Some hassle
    Reviewed Percoceton 10/27/2016I equate the repercussions of taking a percocet to drinking a six-pack of beer, in that I feel similar hang-over effects when I don't take one the next day.
    26
    Man
    Pain (moderate to moderately-severe)
Food
  • Take it with food to lower the chance of an upset stomach.
Kidneys and liver
  • The acetaminophen component in Percocet (Oxycodone / Acetaminophen) can hurt your liver. Using more than 4000 mg of the acetaminophen (or 12 tablets of Percocet (Oxycodone / Acetaminophen) can cause serious harm to your liver that may make you need a liver transplant and can be life-threatening. Don't take more than your doctor prescribes, and avoid other medicines that have acetaminophen when using Percocet (Oxycodone / Acetaminophen).
  • Don't take more than instructed to prevent liver damage.
Pain
  • This is a combination pain medication. It contains both an opioid medicine, and acetaminophen (Tylenol).
  • Works best if you take it as soon as you start feeling pain.
  • Pain relief lasts 4-6 hours.
  • Talk to your doctor if it doesn't work well enough to relieve your pain, or if the side effects are really bad.
  • Combination pain medicine with an opioid component (oxycodone) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
  • Generally considered stronger than Norco or other combination pain medicine for treating pain.
  • Worth it
    Worked well
    Some hassle
    Reviewed Percoceton 9/24/2017Only take what you need. It will usually never take all the pain away. It will help take some pain away, so you can find it at least more tolerable to be productive during the day.
    51
    Woman
    Two years or more
    Pain (moderate to moderately-severe)
  • Worth it
    Didn’t work
    Low hassle
    Reviewed PercocetTake 2 a day for chronic pain. Takes the edge off and I thank God for it. Never increased my dosage. once I n awhile 3 5/325 followed by one the next.
    72
    Woman
  • Not worth it
    Worked so-so
    Low hassle
    Reviewed Percocet Used for breakthrough pain, don't wait till pain gets bad, take immediately
    56
    Woman
Sleep
  • Can help you fall asleep easier.
  • Dizziness and drowsiness is common, but your body may adjust.
  • Worth it
    Worked well
    Some hassle
    Reviewed oxycodone / acetaminophenon 5/26/2021They are additive but, they do get the pain taken of. Tried morphine but, Made me sleep all of the the time... Would rather have the Oxycodones.
    70
    Woman
    Two years or more
    Pain (moderate to moderately-severe)
  • Not worth it
    Worked so-so
    Low hassle
    Reviewed Percoceton 10/26/2016It will make you sleepy
    55
    Woman
    Pain (moderate to moderately-severe)