Pomalyst

(pomalidomide)

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Treats multiple myeloma.

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Our bottom line

Pomalyst (pomalidomide) can work for some people with multiple myeloma who've tried other treatments, but because of its potential harm during pregnancy, it may not be for everyone.

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    $16516.93
Quick facts about Pomalyst
  • Drug class: cancer
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Pomalyst (pomalidomide) is an effective treatment for multiple myeloma when other treatments have failed.
  • Pomalyst (pomalidomide) is taken once daily.
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What to expect from Pomalyst, on one page

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Downsides

  • Pomalyst (pomalidomide) can cause serious fetal harm, and special precautions must be taken throughout treatment to prevent pregnancy.
  • There is a risk of blood clot with this medicine. If you've had a prior blood clot, this medicine may not be for you.
  • Pomalyst (pomalidomide) is not available as generic.
  • Pomalyst (pomalidomide) is only available under a special restricted distribution program which will require monitoring every month before you get refills.
  • Pomalyst (pomalidomide) must be taken with dexamethasone, so if you are unable to take steroids, this medicine is not for you.
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How it works

Pomalyst (pomalidomide) treats multiple myeloma in several ways. It prevents cancer growth, promotes self-destruction of cancer cells, improves your immune system, and lowers inflammation.

Quick facts about Pomalyst
  • Drug class: cancer
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Dosage forms

  • Pill
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Prices and coupons

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What to expect when you take Pomalyst (pomalidomide) for Multiple myeloma

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Low white blood cells
  • Tiredness
  • Low iron
  • Fever
  • Shortness of breath
  • Diarrhea or constipation
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Side effect rates for Pomalyst (pomalidomide)

From 300 clinical trials of Pomalyst when taken for multiple myeloma (4mg (+low dose dexamethasone))
  • Low white blood cells
    51%51%
  • Tiredness
    47%47%
  • Low iron
    30%30%
  • Fever
    27%27%
  • Shortness of breath
    25%25%
  • Diarrhea or constipation
    22%22%
  • Back pain
    20%20%
  • Cough
    20%20%
  • Pneumonia
    19%19%
  • Bone pain
    18%18%
  • Swelling in arms or legs
    17%17%
  • Weakness, numbness, or pain in arms or legs
    17%17%
  • Nausea
    15%15%
  • Muscle spasms
    15%15%
  • Decreased appetite
    13%13%
  • Dizziness
    12%12%
  • Kidney failure
    10%10%
  • Joint pain
    9%9%
  • Vomiting
    8%8%
  • Headache
    8%8%
  • Rash
    8%8%
  • Pain in arms or legs
    7%7%
  • Itchiness
    7%7%
  • Tremor
    6%6%
  • Excessive sweating
    5%5%
  • Pain
    3%3%
  • COPD
    2%2%
  • Fracture
    2%2%
  • Pain in pelvis
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Pomalyst.

Pomalyst (pomalidomide)
Placebo

People taking Pomalyst felt side effect more

People taking Pomalyst felt side effect less

No difference

Risks and Warnings for Pomalyst (pomalidomide)

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    • Higher risk if:
    • Women of childbearing age

    Pomalyst (pomalidomide) can cause severe birth defects and death in unborn babies. Women of reproductive age must have 2 negative pregnancy tests before starting treatment, and take regular tests during treatment. Abstinence or 2 forms of contraception must be used during treatment with Pomalyst (pomalidomide). Pomalyst (pomalidomide) can also be detected in the semen on men. If you are male and have a female partner of child-bearing age, you should always use a condom, including up to 4 weeks after stopping Pomalyst (pomalidomide). If you have questions or concerns, talk to your doctor.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Pomalyst (pomalidomide)

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Price
  • Pomalyst (pomalidomide) can cause very low counts of all blood cells, including those that fight infection and stop bleeding. You will need to have blood tests done to make sure your blood cells don't drop too low, especially when you're first starting to take Pomalyst (pomalidomide). Tell your doctor if you have any infection symptoms (fever, sore throat, or mouth/throat swelling) that don't go away. Talk to your doctor or go to the emergency room right away if you have unusual bleeding that doesn't go away.
Food
  • Take Pomalyst (pomalidomide) with or without food at the same time everyday with a full glass of water. Don't break, chew, or open capsules.