Prandin

(repaglinide)

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Lowers blood sugar.

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Our bottom line

Prandin (repaglinide) works quickly to lower blood sugar, especially during mealtimes. However, it can cause hypoglycemia (low blood sugar) if you are not consistent with your diet and exercise schedule.

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Quick facts about Prandin
  • Drug class: Endocrine
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (repaglinide)

Upsides

  • Quickly and effectively lowers blood sugar during meal times.
  • Less likely to cause hypoglycemia (low blood sugar) than Starlix (nateglinide).
  • Good first-choice if you cannot tolerate metformin or add-on therapy if your blood sugars are not controlled on metformin alone.
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What to expect from Prandin, on one page

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Downsides

  • May cause some weight gain.
  • May cause hypoglycemia (low blood sugar).
  • Can frequently interfere with how other medicines work.
  • Not a good choice if you have poor kidney function, liver problems, or younger than 18 years old.
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What to expect from Prandin, on one page

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How it works

Prandin (repaglinide) stimulates your body to produce more insulin.

Quick facts about Prandin
  • Drug class: Endocrine
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (repaglinide)

Dosage forms

  • Pill
Tried Prandin? Write a review!

Prices and coupons

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What to expect when you take Prandin (repaglinide) for Type 2 diabetes

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Headache
  • Common cold
  • Diarrhea
  • Constipation
  • Urinary tract infection
  • Joint pain
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Side effect rates for Prandin (repaglinide)

From 460 clinical trials of Prandin when taken for type 2 diabetes
  • Low blood sugar
    31%31%
    7%7%
  • Headache
    11%11%
    10%10%
  • Sinusitis
    6%6%
    2%2%
  • Joint pain
    6%6%
    3%3%
  • Nausea
    5%5%
    5%5%
  • Diarrhea
    5%5%
    2%2%
  • Back pain
    5%5%
    4%4%
  • Swelling in arms and legs
    5%5%
  • Heart failure
    4%4%
  • Rhinitis
    3%3%
    3%3%
  • Constipation
    3%3%
    2%2%
  • Vomiting
    3%3%
    3%3%
  • Tingling, numbness, or burning sensation on the skin
    3%3%
    3%3%
  • Chest pain
    3%3%
    1%1%
  • Weight gain
    3%3%
  • Inflammation of the airways
    2%2%
    1%1%
  • Indigestion
    2%2%
    2%2%
  • Urinary tract infection
    2%2%
    1%1%
  • Tooth disorder
    2%2%
  • Allergy
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Prandin.

Prandin (repaglinide)
Placebo

People taking Prandin felt side effect more

People taking Prandin felt side effect less

No difference

Risks and Warnings for Prandin (repaglinide)

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    • Higher risk if:
    • Alcoholism
    • Changes in meal pattern
    • Changes in exercise
    • Insulin
    • Other antidiabetic medications
    • Elderly
    • Bad liver or kidney function

    Prandin (repaglinide) alone or in combination with other diabetic medicines can cause low blood sugar. Very low blood sugar may be life-threatening. Talk to your doctor about the symptoms of low blood sugar, and how to treat it.

Common concerns from people taking Prandin (repaglinide)

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Food
  • If you skip a meal, skip your dose to prevent hypoglycemia (low blood sugar).
  • Quickly and effectively lowers blood sugar during meal times.
Kidneys and liver
  • Not a good choice if you have poor kidney function, liver problems, or younger than 18 years old.
Weight
  • May cause some weight gain.