Prolixin

(fluphenazine)

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Treats schizophrenia and psychosis.

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Our bottom line

Prolixin (fluphenazine) can stabilize your mood. It is used to find the right dose for you before moving to a long-acting injection.

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Quick facts about fluphenazine
  • Drug class: Neuro/psych
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (fluphenazine)

Upsides

  • Good at stabilizing your mood.
  • Available in several oral and injectable forms, including a long-acting injection that is taken less frequently.
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Downsides

  • Can make you sensitive to the sun.
  • Can affect how your body regulates your temperature.
  • Can make it difficult for you to control your movements if you've been on Prolixin (fluphenazine) for a while.
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How it works

Prolixin (fluphenazine) is a derivative of phenothiazine. It regulates dopamine levels in your brain to control psychotic episodes or schizophrenia.

Quick facts about fluphenazine
  • Drug class: Neuro/psych
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (fluphenazine)

Used for

Dosage forms

  • Pill
  • Liquid
  • Injection
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Prices and coupons

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What to expect when you take Prolixin (fluphenazine) for Schizophrenia

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Difficulty controlling movement
  • Muscle spasms
  • Liver damage
  • Increased risk of infections
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Side effect rates for Prolixin (fluphenazine)

Risks and Warnings for Prolixin (fluphenazine)

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    • Higher risk if:
    • › People over 65 with dementia and psychosis

    Older people with dementia and psychosis have a higher risk of death if they take antipsychotic medicines like Prolixin (fluphenazine). They shouldn't be given this medicine.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Pharmacist Q&A

Prolixin (fluphenazine) questions for

Frequently Asked Questions

This medication treats psychotic disorders.

Who is this drug for?

This medication treats psychotic disorders.

Common concerns from people taking Prolixin (fluphenazine)

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Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insertSee pregnancy safe medications
Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for fluphenazine
NUnknown
Alcohol
  • Don't combine with alcohol or narcotics since it can stop your breathing.
Sleep
  • Can make you very sleepy or dizzy. Don't drive or do anything that requires concentration until you know how it affects you.