Prolixin Decanoate

(fluphenazine decanoate)

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Treats schizophrenia or psychosis.

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Our bottom line

Prolixin Decanoate (fluphenazine decanoate) is long-acting medicine for stabilizing your mood that must be given by a trained healthcare professional.

Quick facts about fluphenazine decanoate
  • Drug class: Neuro/psych
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (fluphenazine decanoate)

Upsides

  • Can be given less frequently than the oral, short-acting version.
  • Available in generic.
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Downsides

  • Can make you sensitive to the sun.
  • Can affect how your body regulates your temperature.
  • Can only be used if you're already stable on the short-acting version of this medicine.
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What to expect from fluphenazine decanoate, on one page

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How it works

Prolixin Decanoate (fluphenazine decanoate) is a derivative of phenothiazine. It regulates dopamine levels in your brain to control psychotic episodes or schizophrenia.

Quick facts about fluphenazine decanoate
  • Drug class: Neuro/psych
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (fluphenazine decanoate)

Used for

Dosage forms

  • Injection
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Prices and coupons

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What to expect when you take Prolixin Decanoate (fluphenazine decanoate) for Schizophrenia

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  • Effectiveness
  • Full effects
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  • Possible side effects
  • Difficulty controlling movement
  • Muscle spasms
  • Liver damage
  • Increased risk of infections
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Side effect rates for Prolixin Decanoate (fluphenazine decanoate)

Risks and Warnings for Prolixin Decanoate (fluphenazine decanoate)

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    • Higher risk if:
    • › People over 65 with dementia and psychosis

    Older people with dementia and psychosis have a higher risk of death if they take antipsychotic medicines like Prolixin Decanoate (fluphenazine decanoate). They shouldn't be given this medicine.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Prolixin Decanoate (fluphenazine decanoate)

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Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insertSee pregnancy safe medications
Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for fluphenazine decanoate
NUnknown
Alcohol
  • Don't combine with alcohol or narcotics since it can stop your breathing.
Sleep
  • Can make you very sleepy or dizzy. Don't drive or do anything that requires concentration until you know how it affects you.