propylthiouracil

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Treats overactive thyroid.

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Our bottom line

propylthiouracil works well to treat an overactive thyroid, but it can cause severe liver injury.

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  • Price before coupon
    $69.88
  • Lowest price with coupon
    $27.50
    61% savings
Quick facts about propylthiouracil
  • Drug class: Endocrine
  • Rx status: Prescription only
  • Generic status: Generic only

Upsides

  • propylthiouracil can be used during the first three months of pregnancy.
  • It works just as well as other similar medicines.
  • It's the drug of choice if you have a thyroid storm (life-threatening thyroid problem).
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Downsides

  • You need to take this 3 times a day.
  • propylthiouracil has more severe side effects than the other treatment option.
  • It isn't a permanent treatment for Graves' disease (an overactive thyroid caused by an immune system problem). In some people, the symptoms can come back years later.
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What to expect from propylthiouracil, on one page

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How it works

propylthiouracil stops the conversion of inactive thyroid hormone (T4) to active thyroid hormone (T3).

Quick facts about propylthiouracil
  • Drug class: Endocrine
  • Rx status: Prescription only
  • Generic status: Generic only

Used for

Dosage forms

  • Pill
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Prices and coupons

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What to expect when you take propylthiouracil for Overactive thyroid

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  • First few hoursHours
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  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
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  • Possible side effects
  • Liver injury
  • Skin irritation
  • Stomach pain
  • Nausea
  • Vomiting
  • Skin rash
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Side effect rates for propylthiouracil

Risks and Warnings for propylthiouracil

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  • propylthiouracil can cause serious and life-threatening liver injury. Speak to your doctor right away if you notice a loss of appetite, itchy skin, abdominal pain and swelling, skin and eyes that appear yellow, or bloody stools.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking propylthiouracil

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Kidneys and liver
  • propylthiouracil can cause kidney problems. Speak with your doctor right away if you experience trouble urinating, have low back pain, abdominal swelling and pain, fevers, or blood in your urine.