Pulmozyme

(dornase alfa)

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Thins mucus in lungs in cystic fibrosis.

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Our bottom line

Pulmozyme (dornase alfa) works well to thin your mucus and help you breathe easier, but it is very expensive and requires a nebulizer.

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    $3432.00
Quick facts about Pulmozyme
  • Drug class: Respiratory
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Works well to thin the mucus in your lungs and help clear your airways.
  • Side effects are mild and short-lived.
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What to expect from Pulmozyme, on one page

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Downsides

  • Is very expensive since it's a specialty medicine, and a generic is not available.
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What to expect from Pulmozyme, on one page

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How it works

Pulmozyme (dornase alfa) is an inhaled mucolytic, or mucus thinner. In cystic fibrosis, the DNA from cells in your lungs makes your mucus very thick. This can make it hard to breathe and raises your risk of lung infections. Pulmozyme (dornase alfa) cuts up the DNA to make the mucus loose and thin, which makes it easier to cough up.

Quick facts about Pulmozyme
  • Drug class: Respiratory
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Dosage forms

  • Nebulizer solution
Tried Pulmozyme? Write a review!

Prices and coupons

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What to expect when you take Pulmozyme (dornase alfa) for Cystic fibrosis

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  • First few hoursHours
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  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
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  • Possible side effects
  • Voice changes
  • Sore throat
  • Rash
  • Chest pain
  • Common cold symptoms
  • Pink eye
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Side effect rates for Pulmozyme (dornase alfa)

From 646 clinical trials of Pulmozyme when taken for cystic fibrosis

Risks and Warnings for Pulmozyme (dornase alfa)

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    • Higher risk if:
    • Allergy to dornase alfa or Chinese hamster ovary cell products

    Do not use Pulmozyme (dornase alfa) if you are allergic to dornase alfa or Chinese hamster ovary cell products. Your doctor can help decide if Pulmozyme (dornase alfa) is right for you.