Pylera

(bismuth subcitrate / metronidazole / tetracycline)

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Treats H. pylori infection in the stomach.

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Our bottom line

Pylera (bismuth subcitrate / metronidazole / tetracycline) is an effective treatment for H. pylori infection and is a combination pill making it easier to take compared to other available options.

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  • Lowest price with coupon
    $880.89
Quick facts about Pylera
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Pylera (bismuth subcitrate / metronidazole / tetracycline) is a combination medication so you don't have to take as many pills compared to other treatments available.
  • Takes only 10 days to complete therapy, which is a shorter length of time than alternative options.
  • Good choice for those who have resistance to a class of antibiotics called macrolides, which is also used to treat H.pylori.
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What to expect from Pylera, on one page

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Downsides

  • Pylera (bismuth subcitrate / metronidazole / tetracycline) is not available in generic and can be very expensive.
  • Has interactions with many medicines.
  • Can cause oral birth control pills to be less effective, so you'll need to use a back-up method while taking Pylera (bismuth subcitrate / metronidazole / tetracycline).
  • The medication can increase your sensitivity to sunlight and your risk of getting sunburned.
  • You need to separate multivitamins and supplements, especially ones containing calcium, iron, magnesium, and zinc from Pylera (bismuth subcitrate / metronidazole / tetracycline) by at least a few hours.
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What to expect from Pylera, on one page

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How it works

Pylera (bismuth subcitrate / metronidazole / tetracycline) contains 3 different ingredients that work together to get rid of bacteria in the stomach by preventing them from growing normally as well as causing cell death.

Quick facts about Pylera
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

Dosage forms

  • Pill
Tried Pylera? Write a review!

Prices and coupons

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What to expect when you take Pylera (bismuth subcitrate / metronidazole / tetracycline) for H. pylori

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  • Effectiveness
  • Starts to kick in
    Full effects
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  • Possible side effects
  • Dark stools
  • Nausea
  • Diarrhea
  • Stomach pain
  • Bad taste in mouth
  • Headache
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Side effect rates for Pylera (bismuth subcitrate / metronidazole / tetracycline)

From 147 clinical trials of Pylera when taken for h. pylori infection
  • Dark stools
    16%16%
  • Nausea
    8%8%
  • Diarrhea
    7%7%
  • Stomach pain
    5%5%
  • Headache
    5%5%
  • Bad taste in mouth
    4%4%
  • Indigestion
    3%3%
  • Lack of energy
    3%3%
  • Vaginal infection
    3%3%
  • Dizziness
    3%3%
  • Abnormal lab test
    2%2%
0%
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80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Pylera.

Pylera (bismuth subcitrate / metronidazole / tetracycline)
Placebo

People taking Pylera felt side effect more

People taking Pylera felt side effect less

No difference

Risks and Warnings for Pylera (bismuth subcitrate / metronidazole / tetracycline)

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    • Higher risk if:
    • Using oral birth control pills

    Pylera (bismuth subcitrate / metronidazole / tetracycline) can cause oral forms of birth control to become less effective. You should use a back-up form of birth control such as condoms or vaginal diaphragms while taking this medication to help prevent an unwanted pregnancy.

Common concerns from people taking Pylera (bismuth subcitrate / metronidazole / tetracycline)

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Interactions
  • Has interactions with many medicines.
Alcohol
  • Drinking alcohol while taking Pylera (bismuth subcitrate / metronidazole / tetracycline) can make you feel very sick and cause you to experience symptoms such as nausea, vomiting, headache, and stomach cramps. Don't drink alcohol while you are on this medication and for at least 3 days after stopping Pylera (bismuth subcitrate / metronidazole / tetracycline).