Revatio

(sildenafil)

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Improves breathing in pulmonary arterial hypertension.

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Our bottom line

Revatio (sildenafil) is a first-choice treatment for pulmonary arterial hypertension, but shouldn't be used with some common heart medications.

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Quick facts about Revatio
  • Drug class: Respiratory
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (sildenafil)

Upsides

  • Revatio (sildenafil) is an effective oral medicine for lowering blood pressure in the lungs, and doesn't have many side effects.
  • Available as a lower cost, generic version.
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What to expect from Revatio, on one page

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Downsides

  • Revatio (sildenafil) can cause dizziness during the first few days.
  • Revatio (sildenafil) cannot be combined with some medicines used to treat erectile dysfunction and chest pain.
  • Dose adjusments required for those with kidney or liver disease.
  • Taken three times daily compared to some alternatives taken once daily.
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What to expect from Revatio, on one page

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How it works

Revatio (sildenafil) is a phosphodiesterase-5 enzyme (PDE-5) blocker. It relaxes the arteries in your lungs to relieve pressure and congestion, allowing you to breathe easier.

Quick facts about Revatio
  • Drug class: Respiratory
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (sildenafil)

Used for

  • Pulmonary arterial hypertension

Dosage forms

  • Pill
  • Liquid
Tried Revatio? Write a review!

Prices and coupons

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What to expect when you take Revatio (sildenafil) for Pulmonary arterial hypertension

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  • First few hoursHours
    First few daysDays
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  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
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  • Possible side effects
  • Headache
  • Indigestion
  • Flushing
  • Diarrhea
  • Muscle pain
  • Nose bleed
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Side effect rates for Revatio (sildenafil)

From 139 clinical trials of Revatio when taken for pulmonary arterial hypertension (20 mg three times a day)
  • Headache
    46%46%
    39%39%
  • Indigestion
    13%13%
    7%7%
  • Flushing
    10%10%
    4%4%
  • Nose bleed
    9%9%
    1%1%
  • Diarrhea
    9%9%
    6%6%
  • Difficulty sleeping
    7%7%
    1%1%
  • Difficulty breathing
    7%7%
    3%3%
  • Muscle pain
    7%7%
    4%4%
  • Itchy skin
    6%6%
    1%1%
  • Fever
    6%6%
    3%3%
  • Stuffy nose
    4%4%
  • Stomach inflammation
    3%3%
  • Sinus infection
    3%3%
  • Burning sensation
    3%3%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Revatio.

Revatio (sildenafil)
Placebo

People taking Revatio felt side effect more

People taking Revatio felt side effect less

No difference

Risks and Warnings for Revatio (sildenafil)

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    • Higher risk if:
    • › Taking Revatio (sildenafil) with other blood pressure lowering agents

    Revatio (sildenafil) can lower blood pressure and make you feel dizzy, especially when getting up from a sitting or lying down position. Be careful to avoid lightheadedness and falls. Talk to your doctor if you experience these symptoms and it doesn't go away.

Common concerns from people taking Revatio (sildenafil)

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Price
  • Available as a lower cost, generic version.
Food
  • Be sure to take this medication at the same time every day, with or without food. Don't stop taking Revatio (sildenafil) without talking to your doctor even if you start to feel well.
Kidneys and liver
  • Dose adjusments required for those with kidney or liver disease.
Pain
  • Revatio (sildenafil) cannot be combined with some medicines used to treat erectile dysfunction and chest pain.