Rexulti

(brexpiprazole)

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Helps improve your mood and control your thoughts.

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Our bottom line

Rexulti (brexpiprazole) is an option for people with depression or schizophrenia but it can be more expensive than other medicines.

Lowest price near you
  • Lowest price with coupon
    $1110.20
Quick facts about Rexulti
  • Drug class: Mental health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Rexulti (brexpiprazole) does not cause as much weight gain as other similar medications.
  • Fewer side effects compared to other similar medications.
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What to expect from Rexulti, on one page

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Downsides

  • Avaliable only as brand name and can be more expensive than other options. However, there may be programs to help with co-pays.
  • Rexulti (brexpiprazole) can cause restlessness, especially when you take higher doses and after a long period of time.
  • Can increase your cholesterol, blood sugar, and cause weight gain.
  • Elderly patients with dementia should not take Rexulti (brexpiprazole).
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What to expect from Rexulti, on one page

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How it works

Rexulti (brexpiprazole) is an atypical antipsychotic that changes dopamine and serotonin activity in your brain which can affect thoughts and mood.

Quick facts about Rexulti
  • Drug class: Mental health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Dosage forms

  • Pill
Tried Rexulti? Write a review!

Prices and coupons

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What to expect when you take Rexulti (brexpiprazole) for Schizophrenia

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  • First few daysDays
    First few weeksWeeks
    First few monthsMonths
    Long term
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few daysDays
    First few weeksWeeks
    First few monthsMonths
    Long term
  • Possible side effects
  • Headache
  • Agitation
  • Tremors
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Side effect rates for Rexulti (brexpiprazole)

From 1054 clinical trials of Rexulti when taken for depression (all)
  • Agitation
    9%9%
    2%2%
  • Weight gain
    7%7%
    2%2%
  • Headache
    7%7%
    6%6%
  • Sleepiness
    5%5%
    1%1%
  • Common cold
    4%4%
    2%2%
  • Tremors
    4%4%
    2%2%
  • Fatigue
    3%3%
    2%2%
  • Increased appetite
    3%3%
    2%2%
  • Dizziness
    3%3%
    1%1%
  • Anxiety
    3%3%
    1%1%
  • Restlessness
    3%3%
  • Constipation
    2%2%
    1%1%
  • Decreased cortisol
    2%2%
    1%1%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Rexulti.

Rexulti (brexpiprazole)
Placebo

People taking Rexulti felt side effect more

People taking Rexulti felt side effect less

No difference

Risks and Warnings for Rexulti (brexpiprazole)

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    • Higher risk if:
    • Elderly patients with dementia

    Older patients with dementia-related psychosis have a higher risk of death when treated with antipsychotic medications. Rexulti (brexpiprazole) is not approved to treat dementia-related psychosis. Talk to your doctor if you have questions.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Rexulti (brexpiprazole)

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Price
  • Worth it
    Reviewed Rexultion 9/7/2017The cost
    64
    Woman
    A few months
    Depression
Food
  • Take Rexulti (brexpiprazole) once a day with or without food.
Weight
  • Rexulti (brexpiprazole) can increase your blood sugar and cholesterol and your weight. If you already have high blood sugar or cholesterol, talk to your doctor to see what you can do to stop it from getting worse.
  • Rexulti (brexpiprazole) does not cause as much weight gain as other similar medications.
  • Can increase your cholesterol, blood sugar, and cause weight gain.