Kisqali

(ribociclib)

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Helps treat advanced or metastatic breast cancer.

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Our bottom line

Kisqali (ribociclib) is a first-line endocrine-based therapy for advanced stages of breast cancer in postmenopausal women, but it requires frequent monitoring with blood tests since it can cause some serious side effects.

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    $11880.07
Quick facts about Kisqali
  • Drug class: Cancer
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • New oral anti-cancer treatment that helps delay the progression of disease in breast cancer patients longer than using Femara alone.
  • Has less side effects compared to injectable cancer medications.
  • You only take Kisqali (ribociclib) once a day.
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What to expect from Kisqali, on one page

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Downsides

  • Requires regular monitoring of your heart and liver function.
  • Might not be a good option for those with liver disease.
  • Not a treatment option for those with trouble swallowing since the medication can't be chewed, crushed, or broken.
  • Kisqali (ribociclib) can lower your white blood cell count, which raises your risk of getting infections.
  • Might not be a good medication to use if you already have a history of heart problems.
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What to expect from Kisqali, on one page

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How it works

Kisqali (ribociclib) prevents the normal growth processes of cells, which stops tumors from continuing to develop.

Quick facts about Kisqali
  • Drug class: Cancer
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Advanced or metastatic breast cancer

Dosage forms

  • Pill
Tried Kisqali? Write a review!

Prices and coupons

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What to expect when you take Kisqali (ribociclib) for Breast cancer

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
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  • Possible side effects
  • Low white blood cells (neutrophils)
  • Decreased appetite
  • Nausea
  • Diarrhea
  • Hair loss
  • Tiredness
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Side effect rates for Kisqali (ribociclib)

From 664 clinical trials of Kisqali when taken for breast cancer
  • Low white blood cells (neutrophils)
    75%75%
    5%5%
  • Nausea
    52%52%
    28%28%
  • Tiredness
    37%37%
    30%30%
  • Diarrhea
    35%35%
    22%22%
  • Low white blood cells (leukocytes)
    33%33%
    1%1%
  • Hair loss
    33%33%
    16%16%
  • Vomiting
    28%28%
    16%16%
  • Constipation
    25%25%
    19%19%
  • Headache
    22%22%
    19%19%
  • Back pain
    20%20%
    18%18%
  • Decreased appetite
    19%19%
    15%15%
  • Low red blood cells (anemia)
    18%18%
    5%5%
  • Abnormal liver function tests
    18%18%
    6%6%
  • Rash
    17%17%
    8%8%
  • Itching
    14%14%
    6%6%
  • Fever
    13%13%
    6%6%
  • Sleeping problems
    12%12%
    9%9%
  • Trouble breathing
    12%12%
    9%9%
  • Mouth sores and pain
    12%12%
    7%7%
  • Swelling of the arms or legs
    12%12%
    10%10%
  • Urinary tract infection
    11%11%
    8%8%
  • Low white blood cells (lymphocytes)
    11%11%
    2%2%
  • Stomach pain
    11%11%
    8%8%
0%
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80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Kisqali.

Kisqali (ribociclib)
Placebo

People taking Kisqali felt side effect more

People taking Kisqali felt side effect less

No difference

Risks and Warnings for Kisqali (ribociclib)

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    • Higher risk if:
    • History of heart problems
    • Taking higher doses of Kisqali (ribociclib)
    • Those with abnormal levels of electrolytes

    Kisqali (ribociclib) can interfere with your heart's rhythm and cause an abnormal heartbeat. This is a serious condition that can potentially happen within the first 4 weeks of starting the medication and can be life-threatening if left untreated. Your doctor will monitor your heart rhythm and electrolyte levels before you start and while you are on treatment. If you have a history of certain heart problems, your doctor may choose an alternative treatment option for you.

Common concerns from people taking Kisqali (ribociclib)

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Food
  • Take Kisqali (ribociclib) with or without food. Swallow the pill whole and do not break it in any way.
Kidneys and liver
  • Might not be a good option for those with liver disease.