Edurant

(rilpivirine)

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Works with other medications to treat HIV infection.

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Our bottom line

Edurant (rilpivirine) is a good HIV drug that has to be used in combination with other HIV medications in patients who are new to treatment or are looking for alternatives to a current HIV regimen.

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    $1044.38
Quick facts about Edurant
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Generally well tolerated.
  • Taken only once daily.
  • Edurant (rilpivirine) is available in other combination tablets.
  • Can be used in patients with mild or moderate kidney damage.
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What to expect from Edurant, on one page

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Downsides

  • Must be taken in combination with other HIV drugs to treat HIV. Cannot be taken alone as treatment.
  • Must be taken with a meal.
  • Cannot be taken with proton pump inhibitors (PPI) like Prilosec or Prevacid. If you need to take an acid reducer, try an antacid like calcium carbonate either 2 hours before or 4 hours after Edurant (rilpivirine). Drugs like Pepcid or Zantac (H2RAs) may also be an option, but these should be taken 12 hours before or 4 hours after Edurant (rilpivirine).
  • Not recommended for patients who have a significantly high level of viral cells or have a very low level of immune cells.
  • Not recommended for children under 12 years old.
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What to expect from Edurant, on one page

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How it works

Edurant (rilpivirine) is a Non-nucleoside reverse transcriptase inhibitor (NNRTI). It treats HIV by stopping the virus from replicating within cells in your immune system.

Quick facts about Edurant
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Dosage forms

  • Pill
Tried Edurant? Write a review!

Prices and coupons

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What to expect when you take Edurant (rilpivirine) for Treat HIV

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  • First few hoursHours
    First few daysDays
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  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
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  • Possible side effects
  • Depressive disorders
  • Headache
  • Fatigue
  • Insomnia
  • Rash
  • Abdominal pain
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Side effect rates for Edurant (rilpivirine)

From 686 clinical trials of Edurant when taken for hiv treatment
  • Depressive disorders
    5%5%
  • Headache
    3%3%
  • Insomnia
    3%3%
  • Rash
    3%3%
  • Abdominal pain
    2%2%
  • Fatigue
    2%2%
  • Abnormal dreams
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Edurant.

Edurant (rilpivirine)
Placebo

People taking Edurant felt side effect more

People taking Edurant felt side effect less

No difference

Risks and Warnings for Edurant (rilpivirine)

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    • Higher risk if:
    • History of mental health problems

    Edurant (rilpivirine) has been associated with depression, thoughts of suicide, aggression, and psychosis. If your mood starts to change while taking Edurant (rilpivirine), let your doctor know. If you start thinking about wanting to harm yourself, seek medical attention immediately.

Common concerns from people taking Edurant (rilpivirine)

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Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for Edurant
BProbably safe
Food
  • Take each dose with a meal.
Kidneys and liver
  • Can be used in patients with mild or moderate kidney damage.