Adempas

(riociguat)

Skip to: drug prices sectionSkip to: what to expect sectionSkip to: side effects sectionSkip to: risks and warnings sectionSkip to: common concerns from users and pharmacists
ADVERTISEMENT

Treats high blood pressure in the lungs.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

One of the few pills you can take to treat high blood pressure in the lungs, but it can be expensive.

Quick facts about Adempas
  • Drug class: Respiratory
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Improves your ability to exercise.
  • Less likely to have bad side effects compared to other medicines.
Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Adempas, on one page

Download Fact Sheet
Tried Adempas? Write a review!

Downsides

  • Women must go through a special program to get Adempas (riociguat) because it can cause birth defects.
  • You can't take Adempas (riociguat) with nitrates like nitroglycerin (Nitrostat) or PDE-5 inhibitors like sildenafil because it can lower your blood pressure too much.
  • Not available in generic, so it can be very expensive.
  • You have to take Adempas (riociguat) three times a day, and your doctor might have to change the dose frequently.
Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Adempas, on one page

Download Fact Sheet
How it works

Adempas (riociguat) relaxes blood vessels in the lungs which lowers blood pressure.

Quick facts about Adempas
  • Drug class: Respiratory
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Pulmonary arterial hypertension
  • Chronic thromboembolic pulmonary hypertension

Dosage forms

  • Pill
Tried Adempas? Write a review!

Prices and coupons

Skip prices section. Skip to what to expect section.

What to expect when you take Adempas (riociguat) for Pulmonary arterial hypertension

Skip what to expect section. Skip to side effects section.
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Headache
  • Dizziness
  • Stomach upset
  • Low blood pressure
  • Bleeding
  • Fluid in lungs
Skip side effects section. Skip to risks and warnings section.

Side effect rates for Adempas (riociguat)

From 704 clinical trials of Adempas when taken for cteph and pah
  • Headache
    27%27%
    18%18%
  • Indigestion and stomach pain
    21%21%
    8%8%
  • Dizziness
    20%20%
    13%13%
  • Nausea
    14%14%
    11%11%
  • Diarrhea
    12%12%
    8%8%
  • Low blood pressure
    10%10%
    4%4%
  • Vomiting
    10%10%
    7%7%
  • Low red blood cell count
    7%7%
    2%2%
  • Gastroesophageal reflux disease
    5%5%
    2%2%
  • Constipation
    5%5%
    1%1%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Adempas.

Adempas (riociguat)
Placebo

People taking Adempas felt side effect more

People taking Adempas felt side effect less

No difference

Risks and Warnings for Adempas (riociguat)

Skip risks section. Skip to common concerns section.
    • Higher risk if:
    • Pregnancy

    Women who are able to get pregnant must enroll in a special monitoring program before they can take Adempas (riociguat). Adempas (riociguat) causes birth defects, and women must take regular pregnancy tests and be on birth control while taking it.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Adempas (riociguat)

Final section. Do you want to return to drug navigation?
Price
  • Not sure
    Some hassle
    Reviewed Adempason 2/20/2018The price is something you must check every month.
    72
    Man
    A month or so
    Would rather not say