Savaysa

(edoxaban)

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Prevents blood clots.

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Our bottom line

Savaysa (edoxaban) can prevent blood clots without food restrictions or frequent blood tests. However, its effects will be hard to reverse in the event of an overdose.

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Quick facts about Savaysa
  • Drug class: cardiovascular
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Works as well as other blood thinners to prevent strokes or blood clots.
  • Does not require frequent blood tests like warfarin.
  • Does not require food restrictions like warfarin.
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What to expect from Savaysa, on one page

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Downsides

  • Taking Savaysa (edoxaban) raises your risk of bleeding and bruising. If you take Savaysa (edoxaban) along with other anti-inflammatory medicines like aspirin or ibuprofen, this can make you even more likely to bleed and bruise easily.
  • Savaysa (edoxaban) is not available as a generic medicine so it can be quite pricey.
  • You may not be able to concentrate enough drug in your blood if your kidney works really well. Your doctor should check your kidney function before starting treatment.
  • Savaysa (edoxaban) cannot be used in people with mechanical heart valves or valvular atrial fibrillation.
  • There is no antidote for Savaysa (edoxaban).
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What to expect from Savaysa, on one page

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How it works

Savaysa (edoxaban) is a blood thinner (anticoagulant). It prevents blood clots from forming or growing bigger, which reduces the risk of stroke, and blood clots in people with irregular heart rhythm (nonvalvular atrial fibrillation).

Quick facts about Savaysa
  • Drug class: cardiovascular
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Prevention of stroke and blood clots in nonvalvular atrial fibrillation
  • Treatment of major blood clots (deep vein thrombosis and pulmonary embolism)

Dosage forms

  • Pill
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Prices and coupons

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What to expect when you take Savaysa (edoxaban) for Blood thinning

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Non-major bleeding
  • Rash
  • Anemia
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Side effect rates for Savaysa (edoxaban)

From 5417 clinical trials of Savaysa when taken for prevention of blood clots from atrial fibrillation (60 mg)
  • Major bleeding
    7%7%
  • Bleeding of the stomach
    4%4%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Savaysa.

Savaysa (edoxaban)
Placebo

People taking Savaysa felt side effect more

People taking Savaysa felt side effect less

No difference

Risks and Warnings for Savaysa (edoxaban)

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    • Higher risk if:
    • › Excellent kidney function (filtration rate more than 95 mL/min

    Kidneys filter out waste from your blood. For patients with a very high kidney filtration rate, too much of Savaysa (edoxaban) will be eliminated in the urine. Your doctors should check your kidney function before starting treatment.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Savaysa (edoxaban)

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Price
  • Savaysa (edoxaban) is not available as a generic medicine so it can be quite pricey.
Food
  • Can be taken with or without food.
  • Works as well as other blood thinners to prevent strokes or blood clots.
  • Does not require food restrictions like warfarin.
Kidneys and liver
  • Kidneys filter out waste from your blood. For patients with a very high kidney filtration rate, too much of Savaysa (edoxaban) will be eliminated in the urine. Your doctors should check your kidney function before starting treatment.
  • Savaysa (edoxaban) is filtered by the kidney and liver. If you have kidney or liver problems, talk to your doctor about possibly switching to a different medicine to avoid other side effects.
  • You may not be able to concentrate enough drug in your blood if your kidney works really well. Your doctor should check your kidney function before starting treatment.