Zocor

(simvastatin)

3.8/ 5 average rating with 1176 reviewsforsimvastatin
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Lowers cholesterol.

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Our bottom line

Zocor (simvastatin) is a good medication to improve your cholesterol.

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    $724.79
Quick facts about simvastatin
  • Drug class: Cardiovascular
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (simvastatin)

Upsides

  • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Available in generic.
  • Available in combination pills with other cholesterol medicines.
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What to expect from simvastatin, on one page

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People’s experience with simvastatin

1176reviews so far. What do you think?

Downsides

  • You are at higher risk for side effects if you are female, are 65 years or older, drink alcohol every day, or have liver disease, kidney disease, or diabetes.
  • Not safe to use if you're pregnant.
  • Can have more drug interactions than some other drugs in the same class (statins).
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What to expect from simvastatin, on one page

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How it works

Zocor (simvastatin) is cholesterol-lowering medicine called a statin. It helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).

Quick facts about simvastatin
  • Drug class: Cardiovascular
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (simvastatin)

Used for

Dosage forms

  • Pill
People’s experience with simvastatin

1176reviews so far. What do you think?

Prices and coupons

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What to expect when you take Zocor (simvastatin) for High cholesterol

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  • First few daysDays
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  • Effectiveness
  • Starts to kick in
    Full effects
  • First few daysDays
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    First few monthsMonths
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  • Possible side effects
  • Headache
  • Abdominal pain
  • Bronchitis
  • Muscle pain
  • Liver problems
  • Stomach problems
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Side effect rates for Zocor (simvastatin)

From 4444 clinical trials of simvastatin when taken for high cholesterol (20-40mg/day)
  • Bronchitis
    7%7%
    6%6%
  • Abdominal pain
    6%6%
    6%6%
  • Atrial fibrillation
    6%6%
    5%5%
  • Stomach problems
    5%5%
    4%4%
  • Balance problems
    5%5%
    4%4%
  • Eczema
    5%5%
    3%3%
  • Diabetes
    4%4%
    4%4%
  • Muscle pain
    4%4%
    4%4%
  • Insomnia
    4%4%
    4%4%
  • Edema/swelling
    3%3%
    2%2%
  • Headache
    3%3%
    2%2%
  • Infection, urinary tract
    3%3%
    3%3%
  • Constipation
    2%2%
    2%2%
  • Sinus infection
    2%2%
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of simvastatin.

Zocor (simvastatin)
Placebo

People taking simvastatin felt side effect more

People taking simvastatin felt side effect less

No difference

Risks and Warnings for Zocor (simvastatin)

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    • Higher risk if:
    • Kidney disease
    • High dose of Zocor (simvastatin)
    • Combining Zocor (simvastatin) with other cholesterol-lowering drugs
    • Older age
    • Female gender

    People on Zocor (simvastatin) have reported muscle pain, which may lead to muscle and kidney damage. This is more likely to happen if you take higher doses of Zocor (simvastatin). If you suddenly feel muscle pain, weakness or fever and you haven't been exercising, stop taking Zocor (simvastatin) and talk to your doctor right away.

Common concerns from people taking Zocor (simvastatin)

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Interactions
  • Certain medications can interact with this drug. Talk to your doctor or pharmacist about the medicines you are taking.
  • Can have more drug interactions than some other drugs in the same class (statins).
Alcohol
  • You are at higher risk for side effects if you are female, are 65 years or older, drink alcohol every day, or have liver disease, kidney disease, or diabetes.
Kidneys and liver
  • People on Zocor (simvastatin) have reported muscle pain, which may lead to muscle and kidney damage. This is more likely to happen if you take higher doses of Zocor (simvastatin). If you suddenly feel muscle pain, weakness or fever and you haven't been exercising, stop taking Zocor (simvastatin) and talk to your doctor right away.
  • There are reports of liver damage in people who take Zocor (simvastatin), especially if they are heavy alcohol drinkers or have a history of liver disease. If you notice dark urine or yellowing of the eyes or skin, tell your doctor. Your doctor may also want to check your liver function regularly.
Pain
  • Combining certain medications can increase the risk of muscle pain, muscle damage, and kidney damage. Talk to your doctor or pharmacist when taking any new medications.