Sporanox

(itraconazole)

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Treats fungal infections.

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Our bottom line

Sporanox (itraconazole) is effective oral medication that treats many different kinds of fungal infections. However, it has the potential to interact with a lot of other medications and has a few serious but rare side effects.

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Quick facts about Itraconazole
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (itraconazole)

Upsides

  • Sporanox (itraconazole) is effective in treating infections caused by many different types of fungi.
  • Available as a generic in the capsule form.
  • Sporanox (itraconazole) can be used by people who have kidney problems.
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What to expect from Itraconazole, on one page

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Downsides

  • The liquid solution is especially likely to cause stomach upset like nausea and diarrhea.
  • Sporanox (itraconazole) is not a good choice for simple fungal infections (like nail infections) in people who have congestive heart failure because it can cause high blood pressure and swelling of the limbs.
  • Sporanox (itraconazole) isn't absorbed in the same way by everyone. You'll likely need to get lab tests done to check on its levels in the blood.
  • Sporanox (itraconazole) can cause serious side effects like allergic reactions, liver toxicity, nerve pain, or hearing loss.
  • Sporanox (itraconazole) has a lot of drug interactions. Let your doctor or pharmacist know about all of the medications you're taking.
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What to expect from Itraconazole, on one page

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How it works

Sporanox (itraconazole) kills fungus by preventing it from making its protective cell wall.

Quick facts about Itraconazole
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (itraconazole)

Used for

  • Salvage therapy for invasive aspergillosis
  • Blastomycosis
  • Oropharyngeal and esophageal candidiasis

Dosage forms

  • Pill
  • Liquid
Tried Itraconazole? Write a review!

Prices and coupons

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What to expect when you take Sporanox (itraconazole) for Fungal Infections

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Headache
  • Diarrhea
  • Blurred vision
  • Dizziness
  • Liver toxicity
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Side effect rates for Sporanox (itraconazole)

From 602 clinical trials of Itraconazole when taken for bloodstream fungal infection
  • Nausea
    11%11%
  • Rash
    9%9%
  • Vomiting
    5%5%
  • Swelling due to fluid retention
    4%4%
  • Headache
    4%4%
  • Diarrhea
    3%3%
  • Tiredness
    3%3%
  • Fever
    3%3%
  • Itching
    3%3%
  • High blood pressure
    3%3%
  • Lowered liver function
    3%3%
  • Abdominal pain
    2%2%
  • Dizziness
    2%2%
  • Low potassium
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Itraconazole.

Sporanox (itraconazole)
Placebo

People taking Itraconazole felt side effect more

People taking Itraconazole felt side effect less

No difference

Risks and Warnings for Sporanox (itraconazole)

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    • Higher risk if:
    • › History of congestive heart failure

    Sporanox (itraconazole) shouldn't be used to treat nail fungal infections in people with congestive heart failure as itraconazole because it can make the condition worse.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Sporanox (itraconazole)

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Interactions
  • Sporanox (itraconazole) has many drug interactions and can't be used together with a lot of other medications. Let your doctor or pharmacist know about all of your medications before starting Sporanox (itraconazole).
  • Sporanox (itraconazole) has a lot of drug interactions. Let your doctor or pharmacist know about all of the medications you're taking.
Kidneys and liver
  • Sporanox (itraconazole) can be used by people who have kidney problems.