Stelara

(Ustekinumab)

3.1/ 5 average rating with 50 reviewsforStelara
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Treats moderate to severe psoriasis.

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Our bottom line

Stelara (Ustekinumab) works for two psoriatic conditions. It may be somewhat of a hassle because of the injection, but after the first two doses, you only need to take it every 12 weeks.

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Quick facts about Stelara
  • Drug class: Autoimmune
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Stelara (Ustekinumab) works throughout your whole body (systemic therapy) and may be better than just applying medicine to your skin (local therapy) for moderate or severe plaque psoriasis that covers large areas or many areas of your body.
  • It's used alone or together with another medicine called methotrexate for better results to treat active psoriatic arthritis.
  • Initial dosing might be a hassle, but then you only have to take it every 12 weeks.
  • People treated with Stelara (Ustekinumab) for psoriatic arthritis felt better and had more physical improvement compared to not using the medicine (placebo).
People’s experience with Stelara

50reviews so far. What do you think?

Downsides

  • It's an injection.
  • Stelara (Ustekinumab) lowers your ability to fight infection and can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
  • You have to get your first dose of Stelara (Ustekinumab) at your doctor's office. If you decide not to self-inject and don't have someone to do it for you, you'll need to continue to see your doctor for each dose.
  • You'll need to properly dispose of the needle and syringes in a special (FDA-approved) sharps container.
  • Because Stelara (Ustekinumab) needs to be refrigerated until you use it, if you're traveling, you'll need to carry it in a cooler with an ice pack.
How it works

Stelara (Ustekinumab) is a biologic response modifier, or biologic. It blocks two immune system proteins called IL-12 and IL-23. This slows down new skin cell formation, and lowers inflammation for people with psoriasis or psoriatic arthritis.

Quick facts about Stelara
  • Drug class: Autoimmune
  • Rx status: Prescription only
  • Generic status: No lower cost generic available
People’s experience with Stelara

50reviews so far. What do you think?

Prices and coupons

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Side effect rates for Stelara (Ustekinumab)

  • Immunogenicity
    6%6%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Stelara.

Stelara (Ustekinumab)
Placebo

People taking Stelara felt side effect more

People taking Stelara felt side effect less

No difference

Risks and Warnings for Stelara (Ustekinumab)

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    • Higher risk if:
    • Taking other immunosuppressant drugs
    • Age 60 or older
    • Weak immune system

    Stelara (Ustekinumab) can increase your risk of serious bacterial, fungal and viral infections. In some cases infections can be reactivated from an inactive virus in your body like tuberculosis (TB). You may need to take medicine for TB before you can begin taking Stelara (Ustekinumab). If you develop symptoms of cough, fever, chills, muscle aches, feel very tired, or you notice dark urine, yellowing of skin/eyes, appetite/weight loss, vomiting, change in stool color, stomach discomfort, and skin rash, tell your doctor and get medical care right away.

Pharmacist Q&A

Stelara (Ustekinumab) questions for

Frequently Asked Questions

This medication treats moderate to severe plaque psoriasis in adults who are candidates for phototherapy or systemic therapy.

Who is this drug for?

This medication treats moderate to severe plaque psoriasis in adults who are candidates for phototherapy or systemic therapy.

Common concerns from people taking Stelara (Ustekinumab)

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Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for Stelara
BProbably safe
Interactions
  • There are certain medicines that interact with Stelara (Ustekinumab) or will need the dose adjusted, especially if they are "narrow" therapy medicines like warfarin,