DDAVP

(desmopressin)

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Treats certain bleeding disorders, diabetes insipidus, and bedwetting.

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Our bottom line

DDAVP (desmopressin) can treat several conditions and comes in different forms. Be sure to take DDAVP (desmopressin) the way your doctor tells you to.

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Quick facts about desmopressin
  • Drug class: Endocrine
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (desmopressin)

Upsides

  • DDAVP (desmopressin) is effective at treating bleeding disorders and bedwetting.
  • Available in several forms as a nasal spray, injection, and pill.
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What to expect from desmopressin, on one page

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Downsides

  • DDAVP (desmopressin) can cause you to have dangerously low levels of sodium. Your doctor may tell you to limit how much you drink because too much fluid can make it worse.
  • If you have kidney problems, DDAVP (desmopressin) may not be a good treatment option.
  • Some people find that the DDAVP (desmopressin) nasal spray stops working as well for them after 6 months.
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What to expect from desmopressin, on one page

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How it works

DDAVP (desmopressin) increases proteins in your blood to stop you from bleeding so easily. DDAVP (desmopressin) also works in your kidneys to stop you from urinating too much.

Quick facts about desmopressin
  • Drug class: Endocrine
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (desmopressin)

Used for

Dosage forms

  • Pill
  • Nasal spray
  • Injection
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Prices and coupons

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What to expect when you take DDAVP (desmopressin) for Bleeding or frequent urination

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Headache
  • Abdominal cramps
  • Nausea
  • Changes in blood pressure
  • Low sodium levels
  • Injection site reactions
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Side effect rates for DDAVP (desmopressin)

  • Stomach pain
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of desmopressin.

DDAVP (desmopressin)
Placebo

People taking desmopressin felt side effect more

People taking desmopressin felt side effect less

No difference

Risks and Warnings for DDAVP (desmopressin)

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    • Higher risk if:
    • › Hyponatremia

    DDAVP (desmopressin) can cause dangerously low sodium levels, leading to seizures, coma, respiratory arrest, or death. Your doctor will make sure your sodium levels are normal before you start DDAVP (desmopressin).

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking DDAVP (desmopressin)

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Kidneys and liver
  • DDAVP (desmopressin) can cause or worsen kidney problems. If you already have severe kidney damage, you can't take DDAVP (desmopressin).
  • If you have kidney problems, DDAVP (desmopressin) may not be a good treatment option.
Weight
  • DDAVP (desmopressin) can cause you to hold onto fluids. This can be dangerous if you have heart failure and/or high blood pressure. Talk to your doctor if you have sudden weight gain or swelling in your arms and legs that doesn't go away.