Azulfidine

(Sulfasalazine)

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Reduces inflammation.

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Our bottom line

Azulfidine (Sulfasalazine) is used to treat moderate to severe inflammatory bowel conditions. It's also used with other medicines to treat rheumatoid arthritis.

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    $338.90
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    18%
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Quick facts about Sulfasalazine
  • Drug class: Autoimmune
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (sulfasalazine)

Upsides

  • Can slow down the progression of your rheumatoid arthritis.
  • Helps control your stomach problems if you're taking it for ulcerative colitis.
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Downsides

  • Requires constant lab monitoring, at least every other week when you first start using it.
  • Not a good option if you have kidney or liver disease.
  • If you're allergic to sulfa drugs or aspirin, you can't take Azulfidine (Sulfasalazine).
  • Can interfere with lab test results, so let your doctor know if you're taking this drug.
  • Interacts with a lot of different drugs and can also cause many side effects.
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What to expect from Sulfasalazine, on one page

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How it works

Azulfidine (Sulfasalazine) is an anti-inflammatory drug that reduces inflammation and pain.

Quick facts about Sulfasalazine
  • Drug class: Autoimmune
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (sulfasalazine)

Used for

Dosage forms

  • Pill
  • Extended release
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Prices and coupons

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What to expect when you take Azulfidine (Sulfasalazine) for Ulcerative colitis

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Nausea
  • Vomiting
  • Headache
  • Stomach problems
  • Loss of appetite
  • Reversible male infertility
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Side effect rates for Azulfidine (Sulfasalazine)

  • Nausea
    19%19%
  • Stomach problems
    13%13%
  • Rash
    13%13%
  • Headache
    9%9%
  • Stomach pain
    8%8%
  • Vomiting
    8%8%
  • Fever
    5%5%
  • Dizziness
    4%4%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Sulfasalazine.

Azulfidine (Sulfasalazine)
Placebo

People taking Sulfasalazine felt side effect more

People taking Sulfasalazine felt side effect less

No difference

Risks and Warnings for Azulfidine (Sulfasalazine)

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  • You'll need to get complete blood counts done before starting Azulfidine (Sulfasalazine), and every other week during the first three months of treatment. Since kidney damage can occur, you'll also need a urinalysis and an assessment of your kidney function periodically during treatment. If you notice a sore throat, fever, pale or yellow skin, these may be caused by a serious blood problem or liver damage. Let your doctor know if you have any of these symptoms.

Common concerns from people taking Azulfidine (Sulfasalazine)

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Price
  • Not sure
    Worked so-so
    Low hassle
    Reviewed sulfasalazineon 5/27/2020I had a dramatic drop in my blood platelet count. I also developed a abnormal Red Blood Count. Upon learning that information I was noticing that I was become more tired during the day. I stopped taking the drug and I was in a daze for a few days. I suspected my low red blood count probably had something to do with it.
    73
    Man
    A few months
    Rheumatoid arthritis
Interactions
  • Can interfere with lab test results, so let your doctor know if you're taking this drug.
  • Interacts with a lot of different drugs and can also cause many side effects.
Food
  • Swallow Azulfidine (Sulfasalazine) tablets whole, and take after a meal with a full glass of water. It's important to drink at least 6 glasses of water every day while using Azulfidine (Sulfasalazine).
Kidneys and liver
  • Not a good option if you have kidney or liver disease.