Tagrisso

(osimertinib)

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Treats lung cancer.

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Our bottom line

Tagrisso (osimertinib) is an effective, relatively well-tolerated, oral medication for certain forms of lung cancer that have progressed on other treatments, but is very expensive and may not be available through your local pharmacy.

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    $14522.70
Quick facts about Tagrisso
  • Drug class: cancer
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Tagrisso (osimertinib) is more effective and better tolerated than standard chemotherapy for non-small cell lung cancer with a specific T790M EGFR (epidermal growth factor receptor) mutation.
  • Common side effects are less severe and occur less frequently than other medications used to treat non-small cell lung cancer, such as chemotherapy.
  • Can take Tagrisso (osimertinib) with or without food.
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What to expect from Tagrisso, on one page

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Downsides

  • Limit exposure to the sun, as it can worsen the rash or cause a severe burn.
  • Although rare, Tagrisso (osimertinib) can cause severe lung, heart, and eye problems, and may not be a good choice for everyone.
  • Not a good choice if you are pregnant or planning on getting pregnant, as it can harm your unborn baby.
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What to expect from Tagrisso, on one page

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How it works

Tagrisso (osimertinib) is a tyrosine kinase inhibitor. It targets and blocks a protein involved in cancer cell survival and growth.

Quick facts about Tagrisso
  • Drug class: cancer
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Non-small cell lung cancer

Dosage forms

  • Pill
Tried Tagrisso? Write a review!

Prices and coupons

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What to expect when you take Tagrisso (osimertinib) for Non-small cell lung cancer

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  • First few daysDays
    First few weeksWeeks
    First few monthsMonths
    Long term
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few daysDays
    First few weeksWeeks
    First few monthsMonths
    Long term
  • Possible side effects
  • Diarrhea
  • Rash
  • Dry skin
  • Nail damage/infection/rash
  • Low appetite
  • Cough
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Side effect rates for Tagrisso (osimertinib)

From 279 clinical trials of Tagrisso when taken for non-small cell lung cancer (80 mg)
  • Diarrhea
    41%41%
  • Rash
    34%34%
  • Dry skin
    23%23%
  • Nail damage/infection/rash
    22%22%
  • Tiredness
    22%22%
  • Low appetite
    18%18%
  • Cough
    17%17%
  • Nausea
    16%16%
  • Vomiting
    14%14%
  • Constipation
    14%14%
  • Itchiness
    13%13%
  • Vomiting
    11%11%
  • Back pain
    10%10%
  • Inflamed lung tissue
    3%3%
  • Irregular heartbeat
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Tagrisso.

Tagrisso (osimertinib)
Placebo

People taking Tagrisso felt side effect more

People taking Tagrisso felt side effect less

No difference

Risks and Warnings for Tagrisso (osimertinib)

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  • Rare, serious cases of inflamed lung tissue, called interstitial lung disease or pneumonitis, can occur with Tagrisso (osimertinib), and can be fatal. Talk to your doctor if you have trouble breathing, have trouble catching your breath, cough, or fever.

Common concerns from people taking Tagrisso (osimertinib)

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Food
  • You can take Tagrisso (osimertinib) with or without food.
  • Can take Tagrisso (osimertinib) with or without food.