Vemlidy

(tenofovir alafenamide)

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Treats hepatitis B virus (HBV) infections.

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Our bottom line

Vemlidy (tenofovir alafenamide) decreases liver damage from hepatitis B virus (HBV) and has minimal side effects, but doesn't cure the infection.

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  • Lowest price with coupon
    $1067.70
Quick facts about Vemlidy
  • Drug class: infection
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Vemlidy (tenofovir alafenamide) is a first-choice medicine to treat hepatitis B.
  • Conveniently taken once daily.
  • Compared to Truvada and Viread (tenofovir disoproxil fumarate), Vemlidy (tenofovir alafenamide) is safer for your kidneys and bones.
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What to expect from Vemlidy, on one page

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Downsides

  • Might not be the best choice for people with severe kidney damage.
  • There's not enough evidence to show that Vemlidy (tenofovir alafenamide) can be used safely in children ages 18 or younger.
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What to expect from Vemlidy, on one page

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How it works

Vemlidy (tenofovir alafenamide) is an antiviral (a nucleoside reverse transcriptase inhibitor) that prevents hepatitis B virus from making copies of itself.

Quick facts about Vemlidy
  • Drug class: infection
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Hepatitis B treatment

Dosage forms

  • Pill
Tried Vemlidy? Write a review!

Prices and coupons

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What to expect when you take Vemlidy (tenofovir alafenamide) for Hepatitis B

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Headache
  • Stomach pain
  • Tiredness
  • Cough
  • Nausea
  • Back pain
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Side effect rates for Vemlidy (tenofovir alafenamide)

From 866 clinical trials of Vemlidy when taken for hepatitis b (25mg once daily)
  • Headache
    9%9%
  • Stomach pain
    7%7%
  • Tiredness
    6%6%
  • Cough
    6%6%
  • Nausea
    5%5%
  • Back pain
    5%5%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Vemlidy.

Vemlidy (tenofovir alafenamide)
Placebo

People taking Vemlidy felt side effect more

People taking Vemlidy felt side effect less

No difference

Risks and Warnings for Vemlidy (tenofovir alafenamide)

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    • Higher risk if:
    • Stopping Vemlidy (tenofovir alafenamide)

    Your hepatitis B infection can suddenly get worse if you stop taking Vemlidy (tenofovir alafenamide). Don’t stop taking Vemlidy (tenofovir alafenamide) without talking to your doctor first. After stopping Vemlidy (tenofovir alafenamide), your doctor will check your liver regularly, and there's a chance that you'll need to restart Vemlidy (tenofovir alafenamide). Talk to your doctor right away if you notice any signs of liver problems, like jaundice, dark urine, and yellowing of eyes.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Vemlidy (tenofovir alafenamide)

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Interactions
  • Vemlidy (tenofovir alafenamide) can have significant interactions with many other medications. Don't start or stop any medications without consulting your doctor or pharmacist first.
Kidneys and liver
  • Your hepatitis B infection can suddenly get worse if you stop taking Vemlidy (tenofovir alafenamide). Don’t stop taking Vemlidy (tenofovir alafenamide) without talking to your doctor first. After stopping Vemlidy (tenofovir alafenamide), your doctor will check your liver regularly, and there's a chance that you'll need to restart Vemlidy (tenofovir alafenamide). Talk to your doctor right away if you notice any signs of liver problems, like jaundice, dark urine, and yellowing of eyes.
  • Vemlidy (tenofovir alafenamide) might cause new or worse kidney problems, including kidney failure. The risk is higher if you also take NSAIDs (Motrin/Advil, Aleve, Mobic, etc.), which can also hurt your kidneys. Tell your doctor if you have unexplained weakness or bone pain. Your doctor might order blood and urine tests to check your kidney function and will stop Vemlidy (tenofovir alafenamide) if needed.
  • Compared to Truvada and Viread (tenofovir disoproxil fumarate), Vemlidy (tenofovir alafenamide) is safer for your kidneys and bones.
  • Might not be the best choice for people with severe kidney damage.