Artane

(trihexyphenidyl)

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Treats Parkinson's disease.

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Our bottom line

Artane (trihexyphenidyl) can be used to control tremors if you have Parkinson's, but it can really dry you out and cause other side effects.

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Quick facts about Artane
  • Drug class: Musculoskeletal
  • Rx status:
  • Generic status: Lower-cost generic available (trihexyphenidyl)

Upsides

  • Artane (trihexyphenidyl) can be used with other medicines and in people with advanced Parkinson's who still have tremors.
  • Effective by itself for people under 70 with Parkinson's who only have problems with tremors.
  • Less severe side effects compared to other medicines for tremors.
  • Available as generic.
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Downsides

  • Not recommended in people over 65 or in people with memory problems.
  • Artane (trihexyphenidyl) only calms down tremors because of Parkinson's, but it doesn't treat other symptoms.
  • Can't be used in people with glaucoma or an enlarged prostate.
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How it works

Artane (trihexyphenidyl) blocks acetylcholine in the brain and smooth muscle. This stops muscles from spasming and helps with tremors.

Quick facts about Artane
  • Drug class: Musculoskeletal
  • Rx status:
  • Generic status: Lower-cost generic available (trihexyphenidyl)

Used for

Dosage forms

  • Pill
  • Liquid
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Prices and coupons

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What to expect when you take Artane (trihexyphenidyl) for Parkinson's disease

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  • First few hoursHours
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  • Effectiveness
  • Starts to kick in
    Full effects
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  • Possible side effects
  • Dry mouth
  • Constipation
  • Difficulty urinating
  • Nausea
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Side effect rates for Artane (trihexyphenidyl)

Risks and Warnings for Artane (trihexyphenidyl)

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    • Higher risk if:
    • › Abruptly stopping Artane (trihexyphenidyl)

    In some rare cases, Artane (trihexyphenidyl) can cause neuroleptic malignant syndrome which can be dangerous. This usually happens if you suddenly stop or lower the dose too much. Symptoms include a very high fever, sweating, stiff muscles, and a fast or irregular heartbeat. Call your doctor or 911 right away.

Common concerns from people taking Artane (trihexyphenidyl)

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Food
  • Take Artane (trihexyphenidyl) before meals if you have dry mouth. If you have nausea or stomach irritation, take Artane (trihexyphenidyl) with meals. If Artane (trihexyphenidyl) causes you to drool, take it after meals.
Sleep
  • Taking Artane (trihexyphenidyl) may make you feel dizzy or sleepy for the first few days, especially if you drink a lot of alcohol or take recreational drugs. Your body should adjust to this; however, avoid driving or other activities requiring concentration until you know how your body responds to the medication. Talk to your doctor or pharmacist if these symptoms bother you.