Trilafon
(perphenazine)
Treats schizophrenia.
Our bottom line
Trilafon (perphenazine) is a good medicine for schizophrenia, but it can make you gain weight.
- Price before coupon$56.37
- Lowest price with coupon$18.4067% savings
- Drug class: Neuro/psych
- Rx status: Prescription only
- Generic status: Lower-cost generic available (perphenazine)
Upsides
- Trilafon (perphenazine) can be much cheaper than other medicines.
- Trilafon (perphenazine) is less likely to cause heart problems or changes in blood pressure.
What to expect from perphenazine, on one page
Downsides
- You're more likely to gain weight.
- You can be more sensitive to temperature changes.
- You're more likely to catch colds and flu.
What to expect from perphenazine, on one page
Trilafon (perphenazine) works by blocking dopamine from entering the brain too quickly. Schizophrenia might be caused by your brain being too sensitive to changes in dopamine in your body.
- Drug class: Neuro/psych
- Rx status: Prescription only
- Generic status: Lower-cost generic available (perphenazine)
Used for
Dosage forms
- Pill
Prices and coupons
Skip prices section. Skip to what to expect section.- Pay as low as$16.77Retail priceRetail priceLearn more
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What to expect when you take Trilafon (perphenazine) for Schizophrenia
Skip what to expect section. Skip to side effects section.- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Effectiveness
- Starts to kick inFull effects
- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Possible side effects
- Drowsiness & sleepiness
- Higher risk of infection
- Difficulty controlling movements
It can take time for a drug to start working, or for some side effects to go away.
Source: FDA product label and Iodine pharmacistsSide effect rates for Trilafon (perphenazine)
Manufacturers don’t say how common these side effects are when taking perphenazine for schizophrenia
- Difficulty controlling movements
- Muscle spasms
- Neuroleptic malignant syndrome
- Drowsiness
- Changes in behavior
- Dry mouth
- Nausea and vomiting
- Diarrhea
- Loss of appetite
- Constipation
- Changes in urination
- Skin rashes
- Hives
- Changes in sex drive
- Changes in blood pressure
- Changes in heart rate
- Heart attack
- Higher risk of infection
- Vision changes
- Liver damage
- Swelling in arms and legs
- Fever
- Itching
- Skin sensitivity
- Changes in menstrual periods
Risks and Warnings for Trilafon (perphenazine)
Skip risks section. Skip to common concerns section.- Higher risk if:
- › People age 65 or older with dementia and psychosis
Older people who have dementia and psychosis have a higher risk of death if they take antipsychotic medicines like Trilafon (perphenazine). They shouldn't be given this medicine.
This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.
Common concerns from people taking Trilafon (perphenazine)
Final section. Do you want to return to drug navigation?The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.
Tip: Always talk with your doctor before you take any medication while pregnant.- Don't drink alcohol or take any narcotics while on Trilafon (perphenazine), since it can slow your breathing.
- Trilafon (perphenazine) can make you feel sleepy the first few days that you take it. This can be worse if you drink alcohol or take narcotics for pain or other medical issues. Don't drive or do anything requiring concentration until you know how Trilafon (perphenazine) affects you.
- You're more likely to gain weight.