Acetaminophen with codeine
(acetaminophen / codeine)
Treats mild to moderate pain.
Our bottom line
Acetaminophen with codeine (acetaminophen / codeine) is a good option to treat pain when over-the-counter medicines aren't enough, but don't take too much acetaminophen (Tylenol) since it can hurt your liver.
- Price before coupon$11.11
- Lowest price with coupon$8.25
- Savings26%
- Drug class: Pain
- Rx status: Prescription only
- Generic status: Lower-cost generic available (acetaminophen / codeine)
Upsides
- Combination pain medicine with an opioid component (codeine) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relief in a single pill.
- Provides quick relief for mild to moderate pain.
- Good for as-needed pain and control.
- Generally well tolerated, especially if taken with food to lower risk of stomach upset.
- Lower rates of misuse compared to pure opioid medicines.
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What to expect from Acetaminophen with codeine, on one page
Downsides
- Dizziness and drowsiness is common, but your body may adjust.
- Many people get constipated taking Acetaminophen with codeine (acetaminophen / codeine).
- All opioid containing medicines have the risk of addiction and withdrawal when used long-term.
- Acetaminophen (Tylenol) has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful since many over-the-counter medicines also have acetaminophen.
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What to expect from Acetaminophen with codeine, on one page
Acetaminophen with codeine (acetaminophen / codeine) is a combination pain medicine. Codeine is an opioid (similar to morphine) that works in the brain to lower pain perception. Acetaminophen is a non-opioid pain reliever and fever reducer.
- Drug class: Pain
- Rx status: Prescription only
- Generic status: Lower-cost generic available (acetaminophen / codeine)
Used for
Dosage forms
- Pill
- Liquid
Prices and coupons
Skip prices section. Skip to what to expect section.- Pay as low as$4.05Retail priceRetail priceLearn more
- Kroger PharmacyGet free coupon$8.25
- Get free coupon$8.72
- Get free coupon$8.72
What to expect when you take Acetaminophen with codeine (acetaminophen / codeine) for Pain
Skip what to expect section. Skip to side effects section.- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Effectiveness
- Full effects
- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Possible side effects
- Upset stomach
- Dizziness
- Sleepiness
- Constipation
- Physical dependence
- Difficulty breathing
It can take time for a drug to start working, or for some side effects to go away.
Source: FDA product label and Iodine pharmacistsSide effect rates for Acetaminophen with codeine (acetaminophen / codeine)
Manufacturers don’t say how common these side effects are when taking Acetaminophen with codeine for pain
- Drowsiness
- Sleepiness
- Physical dependence
- Difficulty breathing
- Upset stomach
- Lightheadedness
- Dizziness
- Sedation
- Shortness of breath
- Nausea
- Vomiting
- Allergic reactions
- Euphoria
- Dysphoria
- Constipation
- Abdominal pain
- Itching
- Rash
- Low platelets in the blood
- Low white blood cells
- Respiratory depression
Risks and Warnings for Acetaminophen with codeine (acetaminophen / codeine)
Skip risks section. Skip to common concerns section.- Higher risk if:
- › Alcohol use
- › Taking over-the-counter medicines with acetaminophen
- › History of liver disease
Taking more than 4000mg of acetaminophen per day can cause liver failure or death. Be very careful taking any over-the-counter medicines that have acetaminophen in them. This is more likely to happen if you're a heavy alcohol drinker or you've had liver damage in the past. Talk to your doctor or pharmacist if you have questions.
This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.
Common concerns from people taking Acetaminophen with codeine (acetaminophen / codeine)
Final section. Do you want to return to drug navigation?- Take it with food to lower the chance of an upset stomach.
- Taking more than 4000mg of acetaminophen per day can cause liver failure or death. Be very careful taking any over-the-counter medicines that have acetaminophen in them. This is more likely to happen if you're a heavy alcohol drinker or you've had liver damage in the past. Talk to your doctor or pharmacist if you have questions.
- Children taking codeine for pain after tonsil or adenoid surgery have died because of sudden stopping of breathing. Due to this high risk, codeine is no longer recommended for children. Talk to your doctor if you have any questions.
- Works best if you take it as soon as you start feeling pain.
- Combination pain medicine with an opioid component (codeine) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relief in a single pill.
- Good for as-needed pain and control.
- Worth itLow hassleReviewed Acetaminophen with codeineIt only works great for mild-moderate pain relief. Needed something stronger the 1st mo of my injury.42Woman
- Worth itLow hassleReviewed Acetaminophen with codeineI find it doesnt really get rid of the pain, the pain still hovers there in the background like a friend waving though the window. The codeine just makes you not notice it as much, still worth taking if you live with pain every day.33Man
- Dizziness and drowsiness is common, but your body may adjust.