Acetaminophen with codeine

(acetaminophen / codeine)

3.7/ 5 average rating with 581 reviewsforAcetaminophen with codeine
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Treats mild to moderate pain.

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Our bottom line

Acetaminophen with codeine (acetaminophen / codeine) is a good option to treat pain when over-the-counter medicines aren't enough, but don't take too much acetaminophen (Tylenol) since it can hurt your liver.

Lowest price near you
  • Price before coupon
    $12.36
  • Lowest price with coupon
    $8.25
  • Savings
    33%
Quick facts about Acetaminophen with codeine
  • Drug class: Pain
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (acetaminophen / codeine)

Upsides

  • Combination pain medicine with an opioid component (codeine) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relief in a single pill.
  • Provides quick relief for mild to moderate pain.
  • Good for as-needed pain and control.
  • Generally well tolerated, especially if taken with food to lower risk of stomach upset.
  • Lower rates of misuse compared to pure opioid medicines.
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What to expect from Acetaminophen with codeine, on one page

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People’s experience with Acetaminophen with codeine

581reviews so far. What do you think?

Downsides

  • Dizziness and drowsiness is common, but your body may adjust.
  • Many people get constipated taking Acetaminophen with codeine (acetaminophen / codeine).
  • All opioid containing medicines have the risk of addiction and withdrawal when used long-term.
  • Acetaminophen (Tylenol) has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful since many over-the-counter medicines also have acetaminophen.
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What to expect from Acetaminophen with codeine, on one page

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How it works

Acetaminophen with codeine (acetaminophen / codeine) is a combination pain medicine. Codeine is an opioid (similar to morphine) that works in the brain to lower pain perception. Acetaminophen is a non-opioid pain reliever and fever reducer.

Quick facts about Acetaminophen with codeine
  • Drug class: Pain
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (acetaminophen / codeine)

Used for

Dosage forms

  • Pill
  • Liquid
People’s experience with Acetaminophen with codeine

581reviews so far. What do you think?

Prices and coupons

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What to expect when you take Acetaminophen with codeine (acetaminophen / codeine) for Pain

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  • First few hoursHours
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  • Effectiveness
  • Full effects
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  • Possible side effects
  • Upset stomach
  • Dizziness
  • Sleepiness
  • Constipation
  • Physical dependence
  • Difficulty breathing
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Side effect rates for Acetaminophen with codeine (acetaminophen / codeine)

Risks and Warnings for Acetaminophen with codeine (acetaminophen / codeine)

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    • Higher risk if:
    • Alcohol use
    • Taking over-the-counter medicines with acetaminophen
    • History of liver disease

    Taking more than 4000mg of acetaminophen per day can cause liver failure or death. Be very careful taking any over-the-counter medicines that have acetaminophen in them. This is more likely to happen if you're a heavy alcohol drinker or you've had liver damage in the past. Talk to your doctor or pharmacist if you have questions.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Acetaminophen with codeine (acetaminophen / codeine)

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Food
  • Take it with food to lower the chance of an upset stomach.
Kidneys and liver
  • Taking more than 4000mg of acetaminophen per day can cause liver failure or death. Be very careful taking any over-the-counter medicines that have acetaminophen in them. This is more likely to happen if you're a heavy alcohol drinker or you've had liver damage in the past. Talk to your doctor or pharmacist if you have questions.
Pain
  • Children taking codeine for pain after tonsil or adenoid surgery have died because of sudden stopping of breathing. Due to this high risk, codeine is no longer recommended for children. Talk to your doctor if you have any questions.
  • Works best if you take it as soon as you start feeling pain.
  • Combination pain medicine with an opioid component (codeine) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relief in a single pill.
  • Good for as-needed pain and control.
  • Worth it
    Low hassle
    Reviewed Acetaminophen with codeineIt only works great for mild-moderate pain relief. Needed something stronger the 1st mo of my injury.
    42
    Woman
  • Worth it
    Low hassle
    Reviewed Acetaminophen with codeineI find it doesnt really get rid of the pain, the pain still hovers there in the background like a friend waving though the window. The codeine just makes you not notice it as much, still worth taking if you live with pain every day.
    33
    Man
Sleep
  • Dizziness and drowsiness is common, but your body may adjust.