Viekira XR

(ombitasvir, paritaprevir, ritonavir, and dasabuvir)

Skip to: drug prices sectionSkip to: what to expect sectionSkip to: side effects sectionSkip to: risks and warnings sectionSkip to: common concerns from users and pharmacists
ADVERTISEMENT

A combination of 3 different medicines that treats hepatitis C infection.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) is a once daily drug regimen consisting of 3 pills a day that are effective against genotype 1 hepatitis C virus, but may not be a good option if you have liver problems.

Quick facts about Viekira XR
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Unlike Viekira Pak, Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) is only three pills that is taken all at once.
  • Similar to Viekira Pak, Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) has a 95% to 100% cure rate.
  • Common side effects are manageable and include feeling nauseous, tired, itching, or rash.
  • Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) can also be used to treat genotype 1 hepatitis C if you have a liver transplant.
Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Viekira XR, on one page

Download Fact Sheet
Tried Viekira XR? Write a review!

Downsides

  • Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) is a combination of 3 different medications which may be hard to take if you don't like swallowing a lot of pills.
  • You may need to take an additional medication called ribavirin with Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir).
  • If you are taking ethinyl estradiol-containing medications, you will need another form of birth control during and for 2 weeks after using Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir).
  • Should not be used if you experienced severe rash after taking ritonavir (Norvir).
  • Your doctor will need to take frequent blood tests during the first 4 weeks, and periodically after to monitor your liver function.
Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Viekira XR, on one page

Download Fact Sheet
How it works

Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) is a combination of 3 drugs that stop the hepatitis C virus from making copies in your body. There are three drugs that work directly against the virus.

Quick facts about Viekira XR
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Hepatitis C infection genotype 1

Dosage forms

  • Pill
Tried Viekira XR? Write a review!

What to expect when you take Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) for Hepatitis C infection

Skip what to expect section. Skip to side effects section.
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Nausea
  • Itching
  • Fatigue
  • Skin reactions
Skip side effects section. Skip to risks and warnings section.

Side effect rates for Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir)

From 1025 clinical trials of Viekira XR when taken for hepatitis c infection (12 weeks)
  • Fatigue
    34%34%
    26%26%
  • Nausea
    22%22%
    15%15%
  • Itching
    18%18%
    7%7%
  • Skin reactions
    16%16%
    9%9%
  • Trouble sleeping
    14%14%
    8%8%
  • Weakness/Lack of energy
    14%14%
    7%7%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Viekira XR.

Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir)
Placebo

People taking Viekira XR felt side effect more

People taking Viekira XR felt side effect less

No difference

Risks and Warnings for Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir)

Skip risks section. Skip to common concerns section.
    • Higher risk if:
    • Hepatitis B infection

    Before you can start taking Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir), your doctor will test you for hepatitis B. If you've ever had hepatitis B, taking Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) can cause a hepatitis B infection to start up again, which can be very dangerous if it's not caught in time. Tell your doctor if you've ever been treated for hepatitis B.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir)

Final section. Do you want to return to drug navigation?
Interactions
  • Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) has many drug interactions which can result in more side effects from your medicines or decreased effect of Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir). Be sure to let your doctor know about all of the medicines you are taking. Some of them might have to be changed or stopped altogether.
Alcohol
  • Do not drink alcohol within 4 hours of taking Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir).
Kidneys and liver
  • Before you can start taking Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir), your doctor will test you for hepatitis B. If you've ever had hepatitis B, taking Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) can cause a hepatitis B infection to start up again, which can be very dangerous if it's not caught in time. Tell your doctor if you've ever been treated for hepatitis B.
  • Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) can cause increase an enzyme in your liver called ALT. For women, this is more likely to happen if you are on birth control containing estrogens. These medications should be stopped before starting Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) and you should talk to your doctor about alternative birth control options while you are taking this medication. Speak to your doctor right away if you experience fatigue, weakness, lack of appetite, nausea, yellowing of the eyes, or discolored feces as these may be signs of liver damage.
  • Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) can also be used to treat genotype 1 hepatitis C if you have a liver transplant.