Viibryd

(vilazodone)

●●●●●
4.0/ 5 average rating with 95 reviewsforViibryd
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Treats depression.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Viibryd (vilazodone) is a good option to treat depression, but you can cause stomach irritation including diarrhea.

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    $360.02
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Quick facts about Viibryd
  • Drug class: Mental health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Viibryd (vilazodone) improves depressive symptoms in people with major depressive disorder.
  • The dose of Viibryd (vilazodone) doesn't need to be changed if you have kidney disease.
  • Compared to other antidepressants, it has a lower risk of weight gain and less sexual side effects.
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What to expect from Viibryd, on one page

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People’s experience with Viibryd

95reviews so far. What do you think?

Downsides

  • It may take several weeks before you feel the full effects of Viibryd (vilazodone).
  • Cannot take Viibryd (vilazodone) if you have severe liver problems.
  • Cannot take Viibryd (vilazodone) with other medicines called monoamine oxidase inhibitors (MAOIs).
  • Need to avoid drinking alcohol while taking Viibryd (vilazodone).
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What to expect from Viibryd, on one page

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How it works

Viibryd (vilazodone) is an antidepressant that treats depression by adjusting the levels of serotonin in your brain which helps stabilize your mood.

Quick facts about Viibryd
  • Drug class: Mental health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

Dosage forms

  • Pill
People’s experience with Viibryd

95reviews so far. What do you think?

Prices and coupons

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What to expect when you take Viibryd (vilazodone) for Depression

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Diarrhea
  • Nausea
  • Vomiting
  • Loss of sleep
  • Dry mouth
  • Dizziness
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Side effect rates for Viibryd (vilazodone)

From 1945 clinical trials of Viibryd when taken for depression (40 mg/day)
  • Diarrhea
    28%28%
    10%10%
  • Nausea
    24%24%
    7%7%
  • Headache
    14%14%
    14%14%
  • Dizziness
    8%8%
    5%5%
  • Dry mouth
    7%7%
    5%5%
  • Loss of sleep
    6%6%
    2%2%
  • Vomiting
    5%5%
    2%2%
  • Sleepiness
    5%5%
    2%2%
  • Abdominal pain
    4%4%
    3%3%
  • Low sex drive (males)
    4%4%
  • Upset stomach
    3%3%
    2%2%
  • Gas
    3%3%
    1%1%
  • Abnormal dreams
    3%3%
    2%2%
  • Restlessness
    3%3%
    1%1%
  • Fatigue
    3%3%
    3%3%
  • Increased appetite
    3%3%
    1%1%
  • Erectile dysfunction (males)
    3%3%
    1%1%
  • Stomach infection
    2%2%
    1%1%
  • Tingling and numbness
    2%2%
    1%1%
  • Palpitations
    2%2%
  • Increased weight
    2%2%
    1%1%
  • Abnormal orgasm (males)
    2%2%
  • Ejaculation disorder (males)
    2%2%
  • Low sex drive (females)
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Viibryd.

Viibryd (vilazodone)
Placebo

People taking Viibryd felt side effect more

People taking Viibryd felt side effect less

No difference

Risks and Warnings for Viibryd (vilazodone)

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    • Higher risk if:
    • › Age 24 years or younger

    Viibryd (vilazodone) may increase the risk of suicidal thoughts or behavior. Watch for worsening depression or any unusual changes in mood or behavior, especially during the first few months of treatment or when the dose changes. Report anything concerning to a doctor immediately. Viibryd (vilazodone) is not approved in children under 18.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Viibryd (vilazodone)

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Price
  • Not worth it
    Didn’t work
    Big hassle
    Reviewed Viibrydon 12/3/2020Very expensive ($250 with insurance AND a discount card), MUST take with food or else felt VERY sick, and seemingly caused long periods of constant anger or even fits of RAGE followed by crushing sadness
    23
    Woman
    A month or so
    Depression
  • Worth it
    Worked well
    Low hassle
    Reviewed Viibrydon 3/5/2018Please find a way to lower the cost! Viibryd, has saved my life in many ways, but it is ridiculous what I have to do just to be approved by insurance to get my prescription filled.
    51
    Woman
    Two years or more
    Would rather not say
  • Worth it
    Worked well
    Some hassle
    Reviewed Viibrydon 2/13/2018It works!! however the Cost is so high you must try to get samples from the Dr.Why give me somthing I can not afford to buy???
    61
    Woman
    A few months
    Would rather not say
Alcohol
  • Need to avoid drinking alcohol while taking Viibryd (vilazodone).
  • Not sure
    Worked so-so
    Reviewed Viibrydon 7/31/2017I feel quite frustrated! I have menopause; depression; anxiety; PTSD. I am a recovering alcoholic, drug addict. Can't seem to find the right drug. I don't know if it is menopause, depression, the combination. I feel tired often. I have lost body strength. I cannot maintain stability. I sometimes feel I would be better off dead...or worse start drinking and drugging again to numb out.
    53
    Woman
    A month or so
    Major depressive disorder
Food
  • Take Viibryd (vilazodone) with food at the same time every day.
  • Worth it
    Worked well
    Low hassle
    Reviewed Viibrydon 5/11/2019Take it after your largest meal of the day. No upset stomach!
    52
    Woman
    Two years or more
    Depression
  • Not sure
    Worked well
    Some hassle
    Reviewed vilazodoneon 6/2/2021Take with food or decreased absorption per my MD
    41
    Woman
    A few months
    Depression
  • Worth it
    Worked well
    Low hassle
    Reviewed Viibrydon 2/11/2020Eat food when taking this medication
    31
    Woman
    A year or so
    Depression
Kidneys and liver
  • The dose of Viibryd (vilazodone) doesn't need to be changed if you have kidney disease.
Pain
  • Not sure
    Worked so-so
    Some hassle
    Reviewed Viibrydon 11/1/2019Seems to work. Decreased pain was a bonus. Crazy dreams. Would continue to take but too expensive without insurance.
    51
    Woman
    A year or so
    Depression
Sleep
  • Not sure
    Worked well
    Big hassle
    Reviewed vilazodoneon 9/9/2019I have never experienced sleep issues before until I took Viibryd. I have no diagnosis of bipolar. When I want a goodnights sleep I have found myself opting to skip a few days of my medications.wirks great for depressive thinking but the sleep loss is something I am not dealing well with.
    44
    Woman
    A few months
    Depression
  • Not worth it
    Didn’t work
    Big hassle
    Reviewed Viibrydon 4/12/2019Couldnt sleep . Woke up fearful with bad thoughts everyday. Terrible medicine
    65
    Man
    A few months
    Depression
Weight
  • Worth it
    Worked well
    Some hassle
    Reviewed Viibrydon 10/5/2016All medicine has side effects. Have to weigh the inconvenience of side effects over the inconvenience of being depressed
    37
    Woman
    Major depressive disorder