Vistide

(cidofovir)

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Treats eye infection related to AIDS.

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Vistide (cidofovir) is an injectable medication used to treat an AIDS-related viral infection of the eyes.

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Quick facts about cidofovir
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (cidofovir)

Upsides

  • Vistide (cidofovir) is effective in stopping the virus from multiplying and getting worse.
  • Vistide (cidofovir) is not a daily drug. At the beginning, you'll get a dose once weekly for 2 weeks. After that, you'll get a dose once every 2 weeks.
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What to expect from cidofovir, on one page

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Downsides

  • Vistide (cidofovir) is not a cure for CMV infections of the eye.
  • Very bad kidney problems can happen with Vistide (cidofovir). Your doctor will give you fluids in your vein and a drug called probenecid to lower the chance of kidney problems.
  • Vistide (cidofovir) can potentially cause cancer or birth defects in women who are pregnant.
  • Your doctor may want to get frequent blood tests while taking Vistide (cidofovir) because it can lower your number of white blood cells.
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What to expect from cidofovir, on one page

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How it works

Vistide (cidofovir) works by placing itself into the virus' DNA and slowing it from multiplying in your body.

Quick facts about cidofovir
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (cidofovir)

Used for

  • Cytomegalovirus retinitis
  • Herpes simplex virus (HSV) infection, acyclovir-resistant

Dosage forms

  • Injection
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Prices and coupons

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What to expect when you take Vistide (cidofovir) for CMV retinitis

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Infection
  • Fever
  • Difficulty breathing
  • Nausea / vomiting
  • Injection site reaction
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Side effect rates for Vistide (cidofovir)

Risks and Warnings for Vistide (cidofovir)

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    • Higher risk if:
    • Taking drugs that cause kidney problems
    • History of renal failure
    • ESRD

    Kidney damage is a major concern with Vistide (cidofovir) therapy. Damage can happen with as few as 1 or 2 doses of Vistide (cidofovir). To lower the risk of damage, your doctor will give you fluids and a drug called probenecid before each Vistide (cidofovir) infusion.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Vistide (cidofovir)

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Kidneys and liver
  • Kidney damage is a major concern with Vistide (cidofovir) therapy. Damage can happen with as few as 1 or 2 doses of Vistide (cidofovir). To lower the risk of damage, your doctor will give you fluids and a drug called probenecid before each Vistide (cidofovir) infusion.
  • Very bad kidney problems can happen with Vistide (cidofovir). Your doctor will give you fluids in your vein and a drug called probenecid to lower the chance of kidney problems.