Vivelle-Dot

(Estradiol patch)

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Relieves menopausal symptoms.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Vivelle-Dot (Estradiol patch) is an estrogen patch that may be easier and more convenient to use than the pill or gel form.

Lowest price near you
  • Price before coupon
    $82.89
  • Lowest price with coupon
    $35.00
    58% savings
Quick facts about Vivelle-Dot
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (estradiol patch)

Upsides

  • Good choice if you want to avoid daily dosing of the pill or gel form.
  • Available in wider variety of strengths compared to other estrogen patches.
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What to expect from Vivelle-Dot, on one page

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Downsides

  • Other estrogen patches are dosed once weekly and may be more convenient than Vivelle-Dot (Estradiol patch).
  • Patches can fall off.
  • Estrogen therapy is associated with serious risks for uterine cancer, breast cancer, and blood clots. Don't start treatment until you have had a thorough discussion of the risks and benefits with your doctor.
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What to expect from Vivelle-Dot, on one page

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How it works

Vivelle-Dot (Estradiol patch) is a synthetic hormone that acts like estrogen and restores functions lost during menopause.

Quick facts about Vivelle-Dot
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (estradiol patch)

Used for

  • Hot flashes
  • Vaginal dryness and inflammation
  • Low estrogen

Dosage forms

  • Patch
Tried Vivelle-Dot? Write a review!

Prices and coupons

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What to expect when you take Vivelle-Dot (Estradiol patch) for Postmenopausal estrogen replacement

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Headache
  • Sinus infection
  • Back pain
  • Breast pain
  • Menstrual bleeding
  • Nausea
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Side effect rates for Vivelle-Dot (Estradiol patch)

From 289 clinical trials of Vivelle-Dot when taken for postmenopausal estrogen replacement (0.1 mg/day)
  • Headache
    26%26%
    24%24%
  • Breast pain
    13%13%
  • Back pain
    11%11%
    6%6%
  • Menstrual bleeding
    11%11%
    5%5%
  • Influenza
    8%8%
    9%9%
  • Common cold
    8%8%
    15%15%
  • Nausea
    5%5%
    3%3%
  • Pain
    5%5%
    5%5%
  • Sinus infection
    5%5%
    10%10%
  • Lung infection
    5%5%
    6%6%
  • Neck pain
    5%5%
    1%1%
  • Limb pain
    5%5%
    6%6%
  • Nasal congestion
    5%5%
    5%5%
  • Joint pain
    4%4%
    6%6%
  • Depression
    3%3%
    4%4%
  • Constipation
    2%2%
    3%3%
  • Flu-like symptoms
    2%2%
    6%6%
  • Sinus headache
    2%2%
    5%5%
  • Anxiety
    2%2%
    3%3%
  • Trouble sleeping
    2%2%
    6%6%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Vivelle-Dot.

Vivelle-Dot (Estradiol patch)
Placebo

People taking Vivelle-Dot felt side effect more

People taking Vivelle-Dot felt side effect less

No difference

Risks and Warnings for Vivelle-Dot (Estradiol patch)

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    • Higher risk if:
    • Using estrogen for more than one year

    Vaginal bleeding after menopause can be a warning sign of uterine cancer, so let your doctor know if you notice any unusual bleeding. Using medicines like Vivelle-Dot (Estradiol patch) for more than a year can increase your risk. Talk to your doctor about other medicines you can take with Vivelle-Dot (Estradiol patch) to protect yourself from cancer if you are worried.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect