Zolinza

(vorinostat)

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Helps treat blood cancers of the skin.

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Our bottom line

Zolinza (vorinostat) can possibly help treat your condition if you have failed to respond to 2 other chemotherapy medications, but you will need to do blood tests frequently at least once a month.

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  • Retail price
    $8473.74
  • Savings
    18%
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Quick facts about Zolinza
  • Drug class: Cancer
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Can be a good alternative treatment option when other medications have failed.
  • You only have to take Zolinza (vorinostat) once a day.
  • Zolinza (vorinostat) is available as an oral medication so it is easier to take.
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What to expect from Zolinza, on one page

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Downsides

  • Zolinza (vorinostat) is expensive as it is not available as a generic.
  • Zolinza (vorinostat) has drug interactions with many other prescription medications, vitamins, and supplements.
  • You will need to get blood tests done regularly, at least once a month while you are taking this medication.
  • Can increase the risk of bleeding for people who are also taking blood thinners.
  • Zolinza (vorinostat) raises blood sugar levels so it might not be a good treatment option for diabetics.
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How it works

Zolinza (vorinostat) disrupts the function of enzymes called histone deacetylases, which interferes with the growth of cancer cells ultimately causing them to die.

Quick facts about Zolinza
  • Drug class: Cancer
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Cutaneous T-cell lymphoma

Dosage forms

  • Pill
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Prices and coupons

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What to expect when you take Zolinza (vorinostat) for Cutaneous T-cell lymphoma

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  • First few hoursHours
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  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
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  • Possible side effects
  • Tiredness
  • Diarrhea
  • Nausea
  • Change in taste
  • Decreased platelet count
  • Loss of appetite
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Side effect rates for Zolinza (vorinostat)

From 86 clinical trials of Zolinza when taken for cutaneous t-cell lymphoma (400mg once daily)
  • Tiredness
    52%52%
  • Diarrhea
    52%52%
  • Nausea
    41%41%
  • Change in taste
    28%28%
  • Decreased platelet count
    26%26%
  • Loss of appetite
    24%24%
  • Weight loss
    21%21%
  • Muscle spasms
    20%20%
  • Hair loss
    19%19%
  • Dry mouth
    16%16%
  • Increased blood creatinine
    16%16%
  • Chills
    16%16%
  • Vomiting
    15%15%
  • Constipation
    15%15%
  • Dizziness
    15%15%
  • Low red blood cell count
    14%14%
  • Decreased appetite
    14%14%
  • Abnormal accumulation of fluid
    13%13%
  • Headache
    12%12%
  • Itchy skin
    12%12%
  • Cough
    11%11%
  • Upper respiratory infection
    11%11%
  • Fever
    11%11%
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Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Zolinza.

Zolinza (vorinostat)
Placebo

People taking Zolinza felt side effect more

People taking Zolinza felt side effect less

No difference

Risks and Warnings for Zolinza (vorinostat)

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  • Zolinza (vorinostat) can cause your platelets and red blood cells to drop to abnormally low levels which can be life-threatening. Your cancer doctor will have you do regular blood tests to make sure you're healthy enough to keep taking Zolinza (vorinostat). Tell your doctor right away if you have unusual bleeding or bruising, more tiredness than usual, trouble breathing, or your skin appears pale.

Common concerns from people taking Zolinza (vorinostat)

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Interactions
  • Zolinza (vorinostat) has drug interactions with many other prescription medications, vitamins, and supplements.
Food
  • Take Zolinza (vorinostat) with food.