Vyvanse

(lisdexamfetamine)

3.7/ 5 average rating with 491 reviewsforVyvanse
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Helps you focus and stay alert.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Vyvanse (lisdexamfetamine) is a first-choice treatment for attention-deficit/hyperactivity disorder, but it can be expensive since it's only available as a brand name product.

Lowest price near you
  • Lowest price with coupon
    $301.48
Quick facts about Vyvanse
  • Drug class: Mental health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Vyvanse (lisdexamfetamine) is a first-choice medication to treat attention-deficit/hyperactivity disorder (ADHD).
  • It is usually dosed once a day, so parents don't need to send the medication with their children to school.
  • Can take the capsule as a whole or mix the contents with water, orange juice, or yogurt.
  • Available as a chewable pill form.
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What to expect from Vyvanse, on one page

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People’s experience with Vyvanse

491reviews so far. What do you think?

Downsides

  • Need to take Vyvanse (lisdexamfetamine) in the morning, otherwise it can cause difficulty sleeping at night.
  • Vyvanse (lisdexamfetamine) is not available as a generic medication, so it is expensive.
  • This medicine has the potential for abuse and dependence.
  • Can cause serious side effects for the heart.
  • Can also slow growth in children and cause weight loss.
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What to expect from Vyvanse, on one page

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How it works

Vyvanse (lisdexamfetamine) is an amphetamine stimulant. Researchers don't know exactly how it works for ADHD, but it increases the activity of the hormones norepinephrine and dopamine in the brain, which affects attention and behavior.

Quick facts about Vyvanse
  • Drug class: Mental health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available
People’s experience with Vyvanse

491reviews so far. What do you think?

Prices and coupons

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What to expect when you take Vyvanse (lisdexamfetamine) for Attention deficit hyperactivity disorder (ADHD)

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Weight loss
  • Difficulty sleeping
  • Decreased appetite
  • Dry mouth
  • Irritability
Skip side effects section. Skip to risks and warnings section.

Side effect rates for Vyvanse (lisdexamfetamine)

From 420 clinical trials of Vyvanse when taken for adhd in adults
  • Decreased appetite
    27%27%
    3%3%
  • Difficulty sleeping
    27%27%
    8%8%
  • Dry mouth
    26%26%
    3%3%
  • Diarrhea
    7%7%
  • Nausea
    7%7%
  • Anxiety
    6%6%
  • Loss of appetite
    5%5%
  • Feeling jittery
    4%4%
  • Agitation
    3%3%
  • Increased blood pressure
    3%3%
  • Sweating
    3%3%
  • Restlessness
    3%3%
  • Difficulty breathing
    2%2%
  • Increased heart rate
    2%2%
  • Tremor
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Vyvanse.

Vyvanse (lisdexamfetamine)
Placebo

People taking Vyvanse felt side effect more

People taking Vyvanse felt side effect less

No difference

Risks and Warnings for Vyvanse (lisdexamfetamine)

Skip risks section. Skip to common concerns section.
    • Higher risk if:
    • Taking monoamine oxidase inhibitors (MAOI) 14 days before starting Vyvanse (lisdexamfetamine)

    Vyvanse (lisdexamfetamine) can raise your blood pressure and heartbeat. Talk to your doctor if you have a history of high blood pressure. Tell your doctor right away, if you experience trouble breathing, a bad persisting headache, or chest pain.

Means that some groups have a high risk of experiencing this side effect

Pharmacist Q&A

Vyvanse (lisdexamfetamine) questions for

Frequently Asked Questions

This medication treats ADHD in children, adolescents, and adults.

Who is this drug for?

This medication treats ADHD in children, adolescents, and adults.

Common concerns from people taking Vyvanse (lisdexamfetamine)

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Alcohol
  • Don't take Vyvanse (lisdexamfetamine) with alcohol or illicit drugs.
Food
  • Worth it
    Some hassle
    Reviewed Vyvanseon 2/19/2018I only take it 4 or 5 times out of the week, otherwise I never sleep or eat so I have to take breaks sometimes to make sure I don't constantly lose weight and sleep but it helps me focus so well and gives me motivation to do things so it works really well
    20
    Woman
    Two years or more
    Would rather not say
  • Worth it
    Some hassle
    Reviewed Vyvanseon 5/29/2017Eat with high protein food in the AM.
    37
    Woman
    Two years or more
    ADHD
  • Worth it
    Some hassle
    Reviewed Vyvanseon 3/27/2017Take it as early as possible and eat breakfast prior. You will forget to eat or when you do eat you can't eat much, if any. Take it early to avoid the sleep issues that may pop up.
    21
    Man
    A few months
    ADHD
Sleep
  • Worth it
    Some hassle
    Reviewed Vyvanseon 7/3/2017I miss feeling or feeling tired. Never feel like I get a proper sleep after taking this medication. Also have a very bad "comedown" as the drug is wearing off and if I do not take it the following day
    24
    Woman
    Two years or more
    ADHD
  • Worth it
    Some hassle
    Reviewed Vyvanseon 1/20/2017May interfere with deep sleep. Mild gastrointestinal upset.
    47
    Man
    ADHD
Weight
  • Stimulants, including Vyvanse (lisdexamfetamine), can cause weight loss and slow growth in children. Your doctor will monitor this during treatment. At home, keep close watch of your child's height and weight and report anything unusual to your doctor.
  • Worth it
    Low hassle
    Reviewed Vyvanseon 10/7/2016My 8 year old son is on this for ADHD and he's lost a lot of weight, I'm so upset but it works great for focus.
    46
    Woman
    ADHD