4.3/ 5 average rating with 16 reviewsforXyzal
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Treats allergy symptoms.

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Our bottom line

Xyzal (Levocetirizine) is good for treating allergy symptoms, but it can cause drowsiness.

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Quick facts about Xyzal
  • Drug class: Respiratory
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (levocetirizine)


  • Xyzal (Levocetirizine) is taken once a day to help with allergy symptoms.
  • Available as a generic in both liquid and tablets.
  • Can be taken with or without food.
  • Children can take lower doses of Xyzal (Levocetirizine).
People’s experience with Xyzal

16reviews so far. What do you think?


  • Can cause drowsiness.
  • Don't take Xyzal (Levocetirizine) if you have poor kidney function.
  • Xyzal (Levocetirizine) is similar to Zyrtec, another allergy medication, so if you can't take Zyrtec, you won't be able to take Xyzal (Levocetirizine).
How it works

Xyzal (Levocetirizine) is an antihistamine. It blocks histamine, a chemical that causes congestion, itching, and other allergic reactions.

Quick facts about Xyzal
  • Drug class: Respiratory
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (levocetirizine)
People’s experience with Xyzal

16reviews so far. What do you think?

Prices and coupons

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Side effect rates for Xyzal (Levocetirizine)

From 1982 clinical trials of Xyzal when taken for allergies (5 mg)
  • Somnolence
  • Nasopharyngitis
  • Fatigue
  • Pyrexia
  • Cough
  • Somnolence
  • Dry Mouth
  • Epistaxis
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Xyzal.

Xyzal (Levocetirizine)

People taking Xyzal felt side effect more

People taking Xyzal felt side effect less

No difference

Risks and Warnings for Xyzal (Levocetirizine)

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    • Higher risk if:
    • Taking with alcohol
    • Taking other medicines that make you less alert

    Xyzal (Levocetirizine) lowers your ability to focus, think, and react. Be careful and avoid activities that require you to be alert, such as driving a car or operating machinery, until you know how this medication affects you.

Common concerns from people taking Xyzal (Levocetirizine)

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Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for Xyzal
BProbably safe
  • Can be taken with or without food.
Kidneys and liver
  • Xyzal (Levocetirizine) is processed by the kidney. If you have kidney problems, you may need a different dose to prevent increased risk for side effects. Don't use Xyzal (Levocetirizine) if you have end-stage renal disease or are on hemodialysis. Children ages 6 months to 11 years with kidney problems shouldn't use Xyzal (Levocetirizine).
  • Xyzal (Levocetirizine) can cause dizziness or drowsiness. Don't drink alcohol or take other allergy medications while on this.
  • Can cause drowsiness.
  • Worth it
    Low hassle
    Reviewed Xyzalon 12/19/2016Doesn't really cause drowsiness, I had more drowsiness with Zyrtec than with this one! It actually helps my anaphylaxis even to the point that taking a pill at the beginning of an episode can cause the attack to stop progressing and diminish quickly after the medicine starts to kick in.
    Seasonal allergies
  • Not sure
    Some hassle
    Reviewed Xyzalon 2/15/2018Builds up and makes you progressively more tired, so try 1/4 to 1/2 a tablet dose. Works in a subtle way and is better than Benadryl. Made me VERY prone to anger that was off the charts with this med for me.
    A few months
    Would rather not say
  • Worth it
    Low hassle
    Reviewed Xyzalon 5/10/2019I am not sure that some of the info here is correct. From my studies I found that Zyrtec causes more drowsiness than Xyzal. That is what several other sites say and that was definitely the case for me as well.
    A year or so
    Seasonal allergies