Neupogen

(filgrastim)

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Prevents infection during chemotherapy.

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Our bottom line

Neupogen (filgrastim) can lower your risk of infection during chemotherapy, but it can cause a significant amount of bone pain.

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    $1377.20
Quick facts about Neupogen
  • Drug class: Hematopoietic
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Neupogen (filgrastim) is effective at preventing infection during chemotherapy.
  • There are no dosage adjustments if you have kidney and liver problems.
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What to expect from Neupogen, on one page

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Downsides

  • If you decide not to self-inject and don't have someone to do it for you, you'll need to have your doctor or trained medical staff give you each dose of Neupogen (filgrastim).
  • You'll need to properly dispose of the needle and syringe in a special (FDA-approved) sharps container.
  • Neupogen (filgrastim) is not available as a generic, and is expensive.
  • Neupogen (filgrastim) is injected every day, whereas Neulasta is injected every 10-14 days.
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How it works

Neupogen (filgrastim) is a colony-stimulating factor (blood cell booster) that's similar to a protein your body makes naturally. It works to make a type of white blood cell called neutrophils grow faster, which help your body fight infection.

Quick facts about Neupogen
  • Drug class: Hematopoietic
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Severe chronic neutropenia
  • Febrile neutropenia prophylaxis in myelosuppressive chemotherapy recipients with nonmyeloid malignancies
  • Febrile neutropenia prophylaxis in acute myeloid leukemia (AML) following induction or consolidation chemotherapy

Dosage forms

  • Injection
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Prices and coupons

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What to expect when you take Neupogen (filgrastim) for Infection prevention during chemotherapy treatment

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Decreased platelets
  • Nausea
  • Fever
  • Back pain
  • Dizziness
  • Bone pain
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Side effect rates for Neupogen (filgrastim)

From 451 clinical trials of Neupogen when taken for null
  • Fever
    48%48%
    28%28%
  • Nausea
    43%43%
    32%32%
  • Decreased platelets
    38%38%
    28%28%
  • Fatigue
    20%20%
    10%10%
  • Back pain
    15%15%
    8%8%
  • Dizziness
    14%14%
    3%3%
  • Cough
    14%14%
    8%8%
  • Rash
    14%14%
    5%5%
  • Chest pain
    13%13%
    6%6%
  • Shortness of breath
    13%13%
    8%8%
  • Pain
    12%12%
    6%6%
  • Bone pain
    11%11%
    6%6%
  • Joint pain
    9%9%
    2%2%
  • Pain in extremity
    7%7%
    3%3%
  • Increased blood lactate dehydrogenase
    6%6%
    1%1%
  • Increase blood alkaline phosphatase
    6%6%
    1%1%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Neupogen.

Neupogen (filgrastim)
Placebo

People taking Neupogen felt side effect more

People taking Neupogen felt side effect less

No difference

Risks and Warnings for Neupogen (filgrastim)

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    • Higher risk if:
    • Allergy to Neupogen (filgrastim)

    Some people taking Neupogen (filgrastim) have had hypersensitivity reactions (severe rash, trouble breathing) and angioedema (life-threatening condition with swelling with or without hives). Most cases occur immediately, but can also happen days after you stop the medicine even if you were treated with anti-allergy medicine. If you notice these symptoms after your injection or days later, call your doctor and get medical care right away.

Pharmacist Q&A

Neupogen (filgrastim) questions for

Frequently Asked Questions

Common concerns from people taking Neupogen (filgrastim)

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Food
  • Although rare, Neupogen (filgrastim) can enlarge or rupture (break open) your spleen. A ruptured spleen is very serious and can cause death. Call your doctor and get medical care right away if you have pain in the upper left stomach area or in the shoulder.
Kidneys and liver
  • There are no dosage adjustments if you have kidney and liver problems.
Pain
  • Pain or redness in the area of injection is common. Let your doctor know if you notice a lump, swelling, or bruising that doesn't go away.