Zofran

(Ondansetron)

3.6/ 5 average rating with 366 reviewsforZofran
Skip to: drug prices sectionSkip to: what to expect sectionSkip to: side effects sectionSkip to: risks and warnings sectionSkip to: common concerns from users and pharmacists
ADVERTISEMENT

Helps you feel less queasy.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Zofran (Ondansetron) works well to prevent nausea and vomiting, and it's available in different forms that you don't have to swallow.

Lowest price near you
  • Lowest price with coupon
    $299.28
Quick facts about Zofran
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (ondansetron)

Upsides

  • Available in generic.
  • Available in forms that you don't have to swallow (like a tablet or film that dissolves in your mouth) if you're having trouble keeping anything down.
  • Starts working fast (in 30 minutes.
People’s experience with Zofran

366reviews so far. What do you think?

Downsides

  • Can cause headaches.
  • Can interact with antidepressants.
  • Can only be used to prevent nausea and vomiting, not to treat if it's already happening.
How it works

Zofran (Ondansetron) is an antiemetic (anti-nausea medicine). It works by blocking the nerves that cause your nausea and vomiting reflex.

Quick facts about Zofran
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (ondansetron)

Dosage forms

  • Pill
  • Dissolving tablet
  • Liquid
  • Sublingual film
People’s experience with Zofran

366reviews so far. What do you think?

Prices and coupons

Skip prices section. Skip to what to expect section.
Prices and coupons for 9 (4mg) films of ondansetron near
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
See more prices and coupons in your area
Skip side effects section. Skip to risks and warnings section.

Side effect rates for Zofran (Ondansetron)

From 453 clinical trials of Zofran when taken for nausea/vomiting from chemotherapy (0.45 mg/kg)
  • Headache
    17%17%
    15%15%
  • Diarrhea
    16%16%
    18%18%
  • Constipation
    11%11%
  • Fever
    8%8%
    3%3%
  • Increased AST and ALT
    5%5%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Zofran.

Zofran (Ondansetron)
Placebo

People taking Zofran felt side effect more

People taking Zofran felt side effect less

No difference

Risks and Warnings for Zofran (Ondansetron)

Skip risks section. Skip to common concerns section.
  • Serotonin syndrome is a rare but potentially life-threatening condition caused when there's too much serotonin active in the brain. Your risk goes up if you use Zofran (Ondansetron) with other medications that affect serotonin (other antidepressants, lithium, medications for migraine headaches, and St. John's wort). Symptoms include fast heart rate, sweating, muscle stiffness or spasms, fever, and confusion. Go to the hospital right away if you have symptoms.

Common concerns from people taking Zofran (Ondansetron)

Final section. Do you want to return to drug navigation?
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for Zofran
BProbably safe
Interactions
  • Can interact with antidepressants.
Sleep
  • Worth it
    Low hassle
    Reviewed Zofranon 10/10/2016Will make you tired
    16
    Woman
    Nausea and vomiting after surgery