Zonegran
(zonisamide)
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Controls partial seizures.
Skip Upsides & Downsides section. Skip to side effects section.
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Our bottom line
Zonegran (zonisamide) is used with other medicines to help control partial seizures. It can't be used by itself.
Lowest price near you
- Price before coupon$131.93
- Lowest price with coupon$15.0989% savings
Quick facts about Zonegran
- Drug class: Neuro/psych
- Rx status: Prescription only
- Generic status: Lower-cost generic available (zonisamide)
Upsides
- Available in generic.
- Can be given once a day, so it's easier to remember.
- You can take Zonegran (zonisamide) with or without food.
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What to expect from Zonegran, on one page
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Downsides
- Zonegran (zonisamide) has to be used with other medicines to help control your seizures. It's not used by itself.
- Zonegran (zonisamide) is only approved in people age 16 or older.
- Zonegran (zonisamide) can cause kidney stones; so you have to make sure you drink plenty of liquids.
- Zonegran (zonisamide) can weaken your bones. Talk to your doctor about how to keep your bones strong.
- Other medicines used to control seizures can interact with Zonegran (zonisamide), so your doctor might have to change the dosing of your medications.
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What to expect from Zonegran, on one page
Download Fact SheetHow it works
Zonegran (zonisamide) is a sulfonamide. It's not exactly clear how it controls seizures, but it stops nerves from sending signals that can cause seizures.
Quick facts about Zonegran
- Drug class: Neuro/psych
- Rx status: Prescription only
- Generic status: Lower-cost generic available (zonisamide)
Used for
Dosage forms
- Pill
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Prices and coupons
Skip prices section. Skip to what to expect section.Prices and coupons for 60 (100mg) capsules of zonisamide near
Pay as low as$9.65Retail priceRetail priceLearn more- Kroger PharmacyGet free coupon$15.09
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$16.17 - CostcoGet free coupon$17.55
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See more prices and coupons in your areaWhat to expect when you take Zonegran (zonisamide) for Partial seizures
Skip what to expect section. Skip to side effects section.- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Effectiveness
- Starts to kick inFull effects
- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Possible side effects
- Severe allergic reactions
- Sleepiness
- Suicidal behavior
- Heat stroke
- Dizziness
Side effect rates for Zonegran (zonisamide)
From 499 clinical trials of Zonegran when taken for partial seizures
- Sleepiness17%17%7%7%
- Loss of appetite13%13%6%6%
- Dizziness13%13%7%7%
- Headache10%10%8%8%
- Nausea9%9%6%6%
- Agitation or Irritability9%9%4%4%
- Fatigue8%8%6%6%
- Tiredness7%7%5%5%
- Stomach pain6%6%3%3%
- Difficulty controlling movements6%6%1%1%
- Confusion6%6%3%3%
- Difficulty with concentration6%6%2%2%
- Difficulty with memory6%6%2%2%
- Depression6%6%3%3%
- Trouble sleeping6%6%3%3%
- Double vision6%6%3%3%
- Diarrhea5%5%2%2%
- Speech difficulties5%5%2%2%
- Flu4%4%3%3%
- Difficulty controlling eye movements4%4%2%2%
- Prickling and tingling sensation4%4%1%1%
- Mental slowing4%4%2%2%
- Upset stomach3%3%1%1%
- Weight loss3%3%2%2%
- Anxiety3%3%2%2%
- Skin rash3%3%2%2%
- Constipation2%2%1%1%
- Dry mouth2%2%1%1%
- Bruising2%2%1%1%
- Nervousness2%2%1%1%
- Schizophrenia-like behavior2%2%
- Difficulties in verbal expression2%2%
- Stuffy nose2%2%1%1%
- Changes in taste2%2%
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Where we got our data »
The placebo bar shows how common a side effect was for people taking a sugar pill instead of Zonegran.
Zonegran (zonisamide)
Placebo
People taking Zonegran felt side effect more
People taking Zonegran felt side effect less
No difference
Risks and Warnings for Zonegran (zonisamide)
Skip risks section. Skip to common concerns section.- Higher risk if:
- › Allergy to sulfonamides such as Septra or Bactrim
If you're allergic to sulfa medicines, don’t take Zonegran (zonisamide), since you might have a severe allergic reaction. Talk to your doctor or go to the emergency room right away if you notice a skin rash, high fever, or severe pain in your stomach.
Pharmacist Q&A
Zonegran (zonisamide) questions for
Frequently Asked Questions
Who is this drug for?
This medication treats partial seizures in adults.Common concerns from people taking Zonegran (zonisamide)
Final section. Do you want to return to drug navigation?Alcohol
- Be very careful drinking alcohol or taking medicines for pain or anxiety while taking Zonegran (zonisamide) because your breathing can become dangerously slow.
Food
- You can take Zonegran (zonisamide) with or without food.
Kidneys and liver
- Rarely, Zonegran (zonisamide) can cause changes to the acid balance in your blood. If not treated in time, it can cause kidney stones, or weaken your bones and make them likely to fracture. Your doctor might do regular blood tests to make sure you're healthy.
- Zonegran (zonisamide) can cause kidney stones; so you have to make sure you drink plenty of liquids.
Pain
- If you're allergic to sulfa medicines, don’t take Zonegran (zonisamide), since you might have a severe allergic reaction. Talk to your doctor or go to the emergency room right away if you notice a skin rash, high fever, or severe pain in your stomach.