Zylet

(loteprednol and tobramycin)

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Treats certain eye inflammation and infections.

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Our bottom line

Zylet (loteprednol and tobramycin) is a good choice for certain eye infections and conditions, but isn't for everyone and you can't use it for a long time.

Lowest price near you
  • Lowest price with coupon
    $240.31
Quick facts about Zylet
  • Drug class: Ophthalmic
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Zylet (loteprednol and tobramycin) is very effective at reducing inflammation and treating infection in certain eye conditions.
  • Since Zylet (loteprednol and tobramycin) is applied directly into the eye, you won't experience any severe body side effects.
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What to expect from Zylet, on one page

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Downsides

  • Zylet (loteprednol and tobramycin) is expensive.
  • Taking Zylet (loteprednol and tobramycin) can be burdensome, as you have to use it multiple times a day.
  • There's a limit to how much Zylet (loteprednol and tobramycin) can be used.
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What to expect from Zylet, on one page

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How it works

Zylet (loteprednol and tobramycin) is a combination of loteprednol, a corticosteroid and tobramycin, an antibiotic. Loteprednol blocks chemicals that are responsible for the inflammation response. Tobramycin blocks key proteins in bacteria from being made, resulting in their death.

Quick facts about Zylet
  • Drug class: Ophthalmic
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Steroid responsive eye inflammation conditions
  • Superficial eye infections
  • Blepharitis

Dosage forms

  • Eye drops
Tried Zylet? Write a review!

Prices and coupons

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What to expect when you take Zylet (loteprednol and tobramycin) for Eye inflammation or infection

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Headache
  • Eye stinging
  • Eye burning
  • Eye discharge
  • Eyelid problems
  • Eye deposits
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Side effect rates for Zylet (loteprednol and tobramycin)

  • Headache
    14%14%
  • Increased eye pressures
    10%10%
    4%4%
  • Eye burning
    9%9%
  • Eye stinging
    9%9%
  • Vision problems
    4%4%
  • Eye discharge
    4%4%
  • Eye itching
    4%4%
  • Tearing problems
    4%4%
  • Light sensitivity
    4%4%
  • Eye deposits
    4%4%
  • Eyelid problems
    4%4%
  • Other non-specific eye disorders
    4%4%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Zylet.

Zylet (loteprednol and tobramycin)
Placebo

People taking Zylet felt side effect more

People taking Zylet felt side effect less

No difference

Risks and Warnings for Zylet (loteprednol and tobramycin)

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    • Higher risk if:
    • Taking Zylet (loteprednol and tobramycin) with other steroids

    Since Zylet (loteprednol and tobramycin) contains a steroid, using Zylet (loteprednol and tobramycin) for longer than 10 days can cause your eye pressure to increase, possibly resulting in glaucoma, damage to the optic nerve, and/or vision problems. If you're using Zylet (loteprednol and tobramycin) for longer than 10 days, make sure you're making regular eye doctor appointments and having your eye pressures checked. If you notice changes in vision, talk to your doctor immediately.