Zylet
(loteprednol and tobramycin)
Treats certain eye inflammation and infections.
Our bottom line
Zylet (loteprednol and tobramycin) is a good choice for certain eye infections and conditions, but isn't for everyone and you can't use it for a long time.
- Drug class: Ophthalmic
- Rx status: Prescription only
- Generic status: No lower cost generic available
Upsides
- Zylet (loteprednol and tobramycin) is very effective at reducing inflammation and treating infection in certain eye conditions.
- Since Zylet (loteprednol and tobramycin) is applied directly into the eye, you won't experience any severe body side effects.
Sign up and get Pill Talk, the latest in health & medicine news from Iodine
What to expect from Zylet, on one page
Download Fact SheetDownsides
- Zylet (loteprednol and tobramycin) is expensive.
- Taking Zylet (loteprednol and tobramycin) can be burdensome, as you have to use it multiple times a day.
- There's a limit to how much Zylet (loteprednol and tobramycin) can be used.
Sign up and get Pill Talk, the latest in health & medicine news from Iodine
What to expect from Zylet, on one page
Download Fact SheetZylet (loteprednol and tobramycin) is a combination of loteprednol, a corticosteroid and tobramycin, an antibiotic. Loteprednol blocks chemicals that are responsible for the inflammation response. Tobramycin blocks key proteins in bacteria from being made, resulting in their death.
- Drug class: Ophthalmic
- Rx status: Prescription only
- Generic status: No lower cost generic available
Used for
- Steroid responsive eye inflammation conditions
- Superficial eye infections
- Blepharitis
Dosage forms
- Eye drops
Prices and coupons
Skip prices section. Skip to what to expect section.
Pay as low as$254.08950805664062Retail priceRetail priceLearn more- CostcoGet free coupon$253.32
- Medicine ShoppeGet free coupon$259.91
- Rite AidGet free coupon$264.53
What to expect when you take Zylet (loteprednol and tobramycin) for Eye inflammation or infection
Skip what to expect section. Skip to side effects section.- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Effectiveness
- Starts to kick inFull effects
- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Possible side effects
- Headache
- Eye stinging
- Eye burning
- Eye discharge
- Eyelid problems
- Eye deposits
Side effect rates for Zylet (loteprednol and tobramycin)
- Headache14%14%
- Increased eye pressures10%10%4%4%
- Eye burning9%9%
- Eye stinging9%9%
- Vision problems4%4%
- Eye discharge4%4%
- Eye itching4%4%
- Tearing problems4%4%
- Light sensitivity4%4%
- Eye deposits4%4%
- Eyelid problems4%4%
- Other non-specific eye disorders4%4%
The placebo bar shows how common a side effect was for people taking a sugar pill instead of Zylet.
People taking Zylet felt side effect more
People taking Zylet felt side effect less
Risks and Warnings for Zylet (loteprednol and tobramycin)
Skip risks section. Skip to common concerns section.- Higher risk if:
- › Taking Zylet (loteprednol and tobramycin) with other steroids
Since Zylet (loteprednol and tobramycin) contains a steroid, using Zylet (loteprednol and tobramycin) for longer than 10 days can cause your eye pressure to increase, possibly resulting in glaucoma, damage to the optic nerve, and/or vision problems. If you're using Zylet (loteprednol and tobramycin) for longer than 10 days, make sure you're making regular eye doctor appointments and having your eye pressures checked. If you notice changes in vision, talk to your doctor immediately.