Zyloprim

(allopurinol)

●●●●●
3.7/ 5 average rating with 21 reviewsforAllopurinol
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Lowers uric acid levels in blood, and prevents gout flare-ups.

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Our bottom line

Zyloprim (allopurinol) works well to prevent gout attacks and is cheaper than some alternatives, but it takes a few weeks to start working.

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Quick facts about Allopurinol
  • Drug class: Musculoskeletal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (allopurinol)

Upsides

  • Zyloprim (allopurinol) works well to lower uric acid in the body.
  • It is available as a generic medication.
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What to expect from Allopurinol, on one page

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People’s experience with Allopurinol

21reviews so far. What do you think?

Downsides

  • Zyloprim (allopurinol) can raise the number of gout attacks in the first few weeks.
  • It can take 2 to 6 weeks to feel the full effects of Zyloprim (allopurinol).
  • Kidney stones can form while taking Zyloprim (allopurinol), so you need to drink a lot of fluids to help prevent this.
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What to expect from Allopurinol, on one page

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How it works

Zyloprim (allopurinol) is a xanthine oxidase inhibitor. It lowers uric acid levels in your blood, which can stop gout attacks and kidney stones.

Quick facts about Allopurinol
  • Drug class: Musculoskeletal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (allopurinol)

Used for

Dosage forms

  • Pill
  • Injection
People’s experience with Allopurinol

21reviews so far. What do you think?

Prices and coupons

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What to expect when you take Zyloprim (allopurinol) for Gout

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  • First few daysDays
    First few weeksWeeks
    First few monthsMonths
    Long term
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few daysDays
    First few weeksWeeks
    First few monthsMonths
    Long term
  • Possible side effects
  • Rash
  • Acute gout attack
  • Diarrhea
  • Nausea
  • Liver problems
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Side effect rates for Zyloprim (allopurinol)

Risks and Warnings for Zyloprim (allopurinol)

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  • It is common for people to have more gout attacks the first few weeks they start taking Zyloprim (allopurinol). Talk to your doctor so they can prescribe other medicines to stop the attacks from happening.

Common concerns from people taking Zyloprim (allopurinol)

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Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insertSee pregnancy safe medications
Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for Allopurinol
CWeigh risks vs. benefits
Food
  • Take with food or milk to prevent an upset stomach.
Kidneys and liver
  • Kidney stones can form while taking Zyloprim (allopurinol), so you need to drink a lot of fluids to help prevent this.
  • Worth it
    Worked well
    Low hassle
    Reviewed Allopurinolon 8/29/2017If it was harmful to kidney, not sure.
    66
    Man
    Two years or more
    Gout
Sleep
  • Taking Zyloprim (allopurinol) can make you feel sleepy or dizzy, especially if you're taking other medicines that can also make you feel sleepy, or if you're taking recreational drugs or drinking too much alcohol. Avoid driving or doing other tasks that require concentration until you know how this medication affects you. Get up very slowly from a seated or lying down position.